Human Genetics

, Volume 57, Issue 2, pp 138–141 | Cite as

The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21→qter

  • Donna L. George
  • John A. PhillipsIII
  • Uta Francke
  • Peter H. Seeburg
Original Investigations

Summary

We used a cloned cDNA probe for human growth hormone and Southern blotting techniques to analyze DNA from a series of rodentxhuman somatic cell hybrids for the presence of growth hormone-related sequences. Our results provide evidence for the assignment of the genes for growth hormone and chorionic somatomammotropin as well as a growth hormone-like gene to human chromosome 17. Analysis of mousexhuman hybrid cells containing only part of the long arm of chromosome 17 enabled us to localize these genes to region 17q21→17qter.

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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • Donna L. George
    • 1
  • John A. PhillipsIII
    • 2
  • Uta Francke
    • 3
  • Peter H. Seeburg
    • 4
  1. 1.Department of MedicineThe Howard Hughes Medical Institute Laboratory for Human Biochemical GeneticsBaltimoreUSA
  2. 2.Department of PediatricsThe Johns Hopkins School of MedicineBaltimoreUSA
  3. 3.Department of Human GeneticsYale University School of MedicineNew HavenUSA
  4. 4.Department of Molecular BiologyGenentech, Inc.San FranciscoUSA

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