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Histochemie

, Volume 9, Issue 1, pp 68–77 | Cite as

Osmium tetroxide as a histochemical and histological reagent

  • C. W. M. Adams
  • Y. H. Abdulla
  • O. B. Bayliss
Article

Summary

From the evidence discussed it can be concluded that osmium tetroxide (OsO4) would be reduced to black OsO2 (or an equivalent compound) by the ethylene bonds of liquid or solid cis-unsaturated lipids or by the Δ5-double bond in cholesterol in solid state in tissues. No evidence has been obtained to suggest that OsO4 is either reduced or bound by proteins and polysaccharides in tissue-sections.

Keywords

Public Health Lipid Ethylene Cholesterol Polysaccharide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1967

Authors and Affiliations

  • C. W. M. Adams
    • 1
  • Y. H. Abdulla
    • 1
  • O. B. Bayliss
    • 1
  1. 1.Department of PathologyGuy's Hospital Medical SchoolLondonEngland

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