Diabetologia

, Volume 22, Issue 4, pp 250–253 | Cite as

Seasonal variation in fasting plasma glucose levels in man

  • L. Suarez
  • E. Barrett-Connor
Originals

Summary

A Southern California community study of 4,541 men and women (aged 20–79 years) showed significant seasonal variation in fasting plasma glucose. There was a mean 0.6 mmol/l difference between highest levels in winter and lowest levels in spring. This difference was consistent over a two-year period, similar at all ages and seen in both men and women. Fasting plasma glucose levels correlated directly with percentage possible sunshine (p= 0.03) and inversely with temperature (p= 0.04). Adjustment for the level of measured obesity did not alter the observed association, but a history of recent weight gain corresponded to the season of maximum fasting plasma glucose level.

Key words

Community study fasting plasma glucose obesity seasonal variation 

References

  1. 1.
    National Diabetes Data Group (1979) Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28: 1039–1057Google Scholar
  2. 2.
    Culhane K (1928) The use of rabbits in insulin assay. Q J Pharm 1: 515–533Google Scholar
  3. 3.
    DiMaggio A, Dessauer HC (1963) Seasonal changes in glucose tolerance and glycogen disposition in a lizard. Am J Physiol 204: 677–680Google Scholar
  4. 4.
    Young DAB (1965) Hypothalamic (photoperiodic) control of a seasonal antagonism to insulin in the rat heart. J Physiol 178: 530–543Google Scholar
  5. 5.
    Arvill A, Ahren K (1967) Effects of insulin on the intact levator ani muscle of the rat. Acta Endocrinol 56: 279–294Google Scholar
  6. 6.
    Laurila M, Suomalainen P (1974) Studies in the physiology of the hibernating hedgehog. 19. The changes in the insulin level induced by seasons and hibernation cycle. Ann Acad Sci Fenn Ser A 4 201: 1–40Google Scholar
  7. 7.
    Castex Ch, Donnio R, Sutter BChJ (1979) Seasonal variations in plasma glucose and insulin concentrations after glucose loading in the edible dormouse (Glis glis L.) T Physiol [Paris] 75: 283–288Google Scholar
  8. 8.
    Fahlén M, Odén A, Bjorntorp P, Tibbin G (1971) Seasonal influence on insulin secretion in man. Clin Sci 41: 453–458Google Scholar
  9. 9.
    Campbell IT, Jarrett RJ, Keen H (1975) Diurnal and seasonal variation in oral glucose tolerance: studies in the Antarctic. Diabetologia 11: 139–145Google Scholar
  10. 10.
    Barrett-Connor E (1980) Factors associated with the distribution of fasting plasma glucose in an adult community. Am J Epidemiol 112: 518–523Google Scholar
  11. 11.
    Farinaro E, Stamler J, Upton M, Mojonnier L, Hall Y, Moss D, Berkson DM (1977) Plasma glucose levels: Long-term effect of diet in the Chicago Coronary Prevention Evaluation Program. Ann Intern Med 86: 147–154Google Scholar
  12. 12.
    Himsworth HP (1935) The dietetic factor determining the glucose tolerance and sensitivity to insulin of healthy men. Clin Sci 2: 67–94Google Scholar
  13. 13.
    Grey N, Kipnis DM (1971) Effect of diet composition on the hyper-insulinemia of obesity. N Engl J Med 285: 827–831Google Scholar
  14. 14.
    Munoz JM, Sandstead HH, Jacob RA (1979) Effects of dietary fiber on glucose tolerance in normal men. Diabetes 28: 496–502Google Scholar
  15. 15.
    Vranic M, Berger M (1979) Exercise and diabetes mellitus. Diabetes 28: 147–163Google Scholar
  16. 16.
    Johnson RE, Kark RM (1947) Environment and food intake in man. Science 105: 378–379Google Scholar
  17. 17.
    den Hartog C, van Schaik TFSM, Dalderup LM, Drion EF, Mulder T (1965) The diet of volunteers participating in a longterm epidemiological field survey on coronary heart disease at Zutphen the Netherlands. Voeding 26: 184–208Google Scholar
  18. 18.
    Marr JW (1967) Seasonal differences in the diets of male bank staff. In: Kühnau J (ed) Seventh International Congress of Nutrition, vol 5. Friedrich Vieweg Verlag, Braunschweig, p 39.Google Scholar
  19. 19.
    Zahorska-Markiewicz B (1980) Weight reduction and seasonal variation. Int J Obes 4: 139–143Google Scholar
  20. 20.
    Kuroshima A, Doi K, Ohno T (1979) Seasonal variation of plasma glucagon concentrations in men. Jpn J Physiol 29: 661–668Google Scholar
  21. 21.
    Campbell IT, Jarrett RJ, Rutland P, Stimmler E (1975) The plasma insulin and growth hormone response to oral glucose: diurnal and seasonal observations in the Antarctica. Diabetologia 11: 147–150Google Scholar

Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • L. Suarez
    • 1
  • E. Barrett-Connor
    • 1
  1. 1.Departments of Community and Family Medicine and MedicineSchool of Medicine, University of CaliforniaSan DiegoUSA

Personalised recommendations