Journal of Mathematical Biology

, Volume 21, Issue 3, pp 383–388 | Cite as

Cell spreading and motility: A model lamellipod

  • George F. Oster
  • Alan S. Perelson
Research Announcement


Cells moving in vitro do so by means of a motile appendage, the lamellipod. This is a broad, flat sheet of cytogel which spreads in front of the cell and pulls the cell forward. We present here a mathematical model for lamellipodial motion based on the physical chemistry of actomyosin gels.

Key words

Cell motility mechanochemistry cytogel 


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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • George F. Oster
    • 1
  • Alan S. Perelson
    • 2
  1. 1.Department of BiophysicsUniversity of CaliforniaBerkeleyUSA
  2. 2.Theoretical DivisionLos Alamos National LaboratoryLos AlamosUSA

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