Diabetologia

, Volume 24, Issue 1, pp 13–15 | Cite as

Free and lipid inositol, sorbitol and sugars in sciatic nerve obtained post-mortem from diabetic patients and control subjects

  • J. A. Mayhew
  • K. R. W. Gillon
  • J. N. Hawthorne
Originals

Summary

Sciatic nerves removed post-mort`em from diabetic patients and normal subjects were analysed by gas chromatography for glucose, fructose, sorbitol and myo-inositol. The concentrations of free and lipid inositol were significantly lower in nerves from the diabetic than from the control group. Concentrations of glucose, fructose and sorbitol were higher in the nerves of the diabetic patients.

Key words

Myo-inositol sorbitol diabetes sciatic nerve postmortem diabetic neuropathy 

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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • J. A. Mayhew
    • 1
  • K. R. W. Gillon
    • 2
  • J. N. Hawthorne
    • 2
  1. 1.Department of Clinical ChemistryCity Hospital, University Hospital and Medical SchoolNottinghamUK
  2. 2.Department of BiochemistryUniversity Hospital and Medical SchoolNottinghamUK

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