, Volume 24, Issue 1, pp 10–12 | Cite as

Diabetic nephropathy and arterial hypertension

  • H. -H. Parving
  • A. R. Andersen
  • U. M. Smidt
  • B. Oxenbøll
  • B. Edsberg
  • J. Sandahl Christiansen


The relationship between arterial blood pressure and diabetic nephropathy was examined in 61 Type 1 (insulin-dependent) diabetic patients (22 females and 39 males). All patients fulfilled the following criteria: persistent proteinuria (>0.5g/day), onset of diabetes before 31 years of age, age <42 years, serum creatinine <130 μmol/l, and no antihypertensive treatment. Thirty Type 1 diabetic patients without persistent proteinuria but matched for sex, age, ideal body weight and duration of diabetes, and 30 healthy subjects matched for sex, age and ideal body weight were also studied as controls. The diabetic patients with persistent proteinuria had elevated blood pressures (146/96±17/10 mmHg, mean±SD) compared with 123/75±11/8 mmHg in diabetic patients without persistent proteinuria, and normal subjects (120/77±6/6 mmHg; p<0.001 for each). Diastolic blood pressure ⩾95 mmHg was found in 51% of the group with persistent proteinuria. Elevated arterial blood pressure is frequently present in young Type 1 diabetic patients with diabetic nephropathy and normal serum creatinine.

Key words

Type 1 diabetes diabetic nephropathy hypertension proteinuria serum creatinine 


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Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • H. -H. Parving
    • 1
    • 2
    • 5
  • A. R. Andersen
    • 1
    • 3
  • U. M. Smidt
    • 5
  • B. Oxenbøll
    • 1
  • B. Edsberg
    • 4
  • J. Sandahl Christiansen
    • 1
  1. 1.Steno Memorial HospitalGentofteDenmark
  2. 2.Department of Medicine FHerlev Hospital, University of CopenhagenCopenhagenDenmark
  3. 3.Department of Medicine BHerlev Hospital, University of CopenhagenCopenhagenDenmark
  4. 4.Department of Medicine CBispebjerg HospitalCopenhagenDenmark
  5. 5.Department of Clinical PhysiologyBispebjerg HospitalCopenhagenDenmark

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