, Volume 30, Issue 10, pp 824–824 | Cite as

Low C4 levels in Type 1 (insulin-dependent) diabetes

  • C. H. Mijovic
  • J. A. Fletcher
  • A. R. Bradwell
  • A. H. Barnett
Letters to the Editor


Public Health Internal Medicine Human Physiology Metabolic Disease 
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    Charlesworth JA, Timmermans V, Golding J, Campbell LV, Peake PW, Pussel PA, Wakefield D, Howard N (1987) Complement in Type 1 diabetes. Diabetologia 30: 372–379Google Scholar
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    Awdeh ZL, Raum D, Alper CA (1979) Genetic polymorphism of human complement C4 and detection of hétérozygotes. Nature 282: 205–207Google Scholar
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    Raum D, Awdeh Z, Yunis EJ, Alper CA, Gabbay KH (1984) Extended major histocompatibility complex haplotypes in Type 1 diabetes mellitus. J Clin Invest 74: 449–454Google Scholar
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    Carroll MC, Palsdottir A, Belt KT, Porter RR (1985) Deletion of complement C4 and steroid 21-hydroxylase genes in the HLA class III region. EMBO J 4: 2547–2552Google Scholar
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    Mijovic C, Fletcher J, Bradwell AR, Harvey T, Barnett AH (1985) Relation of gene expression (allotype) of the fourth component of complement to insulin dependent diabetes and its microangiopathic complications. Br Med J 291: 9–10Google Scholar

Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • C. H. Mijovic
    • 1
  • J. A. Fletcher
  • A. R. Bradwell
  • A. H. Barnett
  1. 1.Immuno Diagnostic Research Laboratory Department of ImmunologyThe Medical SchoolBirminghamUK

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