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Human Genetics

, Volume 66, Issue 1, pp 66–70 | Cite as

A new form of hypertrichosis inherited as an X-linked dominant trait

  • M. A. Macías-Flores
  • D. García-Cruz
  • H. Rivera
  • M. Escobar-Luján
  • A. Melendrez-Vega
  • D. Rivas-Campos
  • F. Rodríguez-Collazo
  • I. Moreno-Arellano
  • J. M. Cantu
Original Investigations

Summary

A family with a distinct form of congenital generalized hypertrichosis was studied. Males were more severely affected than females, who exhibited asymmetric hair distribution. This finding was attributed to lyonization, since genealogical studies indicated an X-linked pattern of inheritance. A back mutation is postulated as the origin of this new phenotype.

Keywords

Internal Medicine Metabolic Disease Distinct Form Dominant Trait Hypertrichosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • M. A. Macías-Flores
    • 1
    • 2
  • D. García-Cruz
    • 1
    • 2
  • H. Rivera
    • 1
    • 2
  • M. Escobar-Luján
    • 1
    • 2
  • A. Melendrez-Vega
    • 1
    • 2
  • D. Rivas-Campos
    • 1
    • 2
  • F. Rodríguez-Collazo
    • 1
    • 2
  • I. Moreno-Arellano
    • 1
    • 2
  • J. M. Cantu
    • 1
    • 2
  1. 1.Escuela de MedicinaUniversidad Autónoma de ZacatecasZacatecasMexico
  2. 2.División de Genética, Subjefatura de Investigación Científica, Unidad de Investigación Biomédica, Centro Médico de OccidenteInstituto Mexicano del Seguro SocialGuadalajaraMexico

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