Experimental Brain Research

, Volume 77, Issue 2, pp 432–436 | Cite as

The response variability of striate cortical neurons in the behaving monkey

  • R. Vogels
  • W. Spileers
  • G. A. Orban
Research Note


In order to relate single cell performance to behavioral discrimination one needs measurements of the response variance of the units. We recorded from 183 single units of area V1 of monkeys performing an orientation discrimination task. The response variance was found to increase with increasing response strength. This relationship between response variance and response strength was well described by a power function with a power close to one. The response variance was on average 1.9 times the response strength. Despite important differences in preparation, the behaving monkey data are in good agreement with those previously obtained in paralysed and anesthetised animals.

Key words

Visual cortex Single cell Response variability Behaving monkey 


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  1. Bradley A, Skottun BC, Ohzawa I, Sclar G, Freeman R (1987) Visual orientation and spatial frequency discrimination: a comparison of single neurons and behavior. J Neurophysiology 57:755–772Google Scholar
  2. Coenen AML, Vendrik AJH (1972) Determination of the transfer ratio of cat's geniculate neurones through quasiintracellular recordings and the relation with levels of alertness. Exp Brain Res 14:227–242Google Scholar
  3. Dean AF (1981) The variability of discharge of simple cells in cat striate cortex. Exp Brain Res 44:437–440Google Scholar
  4. Heggelund P, Albus K (1978) Response variability and orientation discrimination of single cells in striate cortex of cat. Exp Brain Res 32:197–211Google Scholar
  5. Ikeda H, Wright MJ (1974) Sensitivity of neurones in visual cortex under different levels of anesthesia. Exp Brain Res 20:417–484Google Scholar
  6. Judge SJ, Richmond BJ, Chu FC (1980) Implantation of magnetic search coils for measurement of eye positions: an improved method. Vision Res 20:535–538Google Scholar
  7. Liebovitch LS, Fishbarch J, Koniarek JP (1987) Ion channel kinetics: a model based on fractal scaling rather than multistate Markov processes. Math Biosci 84:37–68Google Scholar
  8. Livingstone MS, Hubel DH (1981) Effects of sleep and arousal in the processing of visual information in the cat. Nature 291:554–561Google Scholar
  9. Maffei L, Rizzolatti GT (1965) Effects of synchronizing sleep on the responses of lateral geniculate units to flashes of light. Archs Ital Biol 103:609–622Google Scholar
  10. Noda H, Freeman RB Jr, Creutzfeldt OD (1972) Neuronal correlates of eye movements in the visual cortex of the cat. Science 175:661–664Google Scholar
  11. Orban GA, Devos M, Vogels R (1989) Cheapmonkey: comparing an ANN and the primate brain on a simple perceptual task — orientation discrimination. Proceedings NATO ARW Neurocomputing, algorithms, architectures and applications (in press)Google Scholar
  12. Perkel DH, Gerstein GL, Moore GP (1967) Neuronal spike trains and stochastic point processes. I. The single spike train. Biophys J 7:392–418Google Scholar
  13. Schiller PH, Finlay BL, Volmann SF (1976) Short-term response variability of monkey striate neurons. Brain Res 105:347–349Google Scholar
  14. Snedecor GW, Cochran WG (1980) Statistical methods. The Iowa State University PressGoogle Scholar
  15. Suzuki H, Azuma M (1976) A glass insulated ‘Elgiloy’ microelectrode for recording unit activity in chronic monkey experiments. EEG Clin Neurophysiology 41:93–95Google Scholar
  16. Tolhurst DJ, Movshon JA, Thompson ID (1981) The dependence of response amplitude and variance of cat visual cortical neurones on stimulus contrast. Exp Brain Res 41:414–419Google Scholar
  17. Tolhurst DJ, Movshon JA, Dean AF (1983) The statistical reliability of signals in single neurons in cat and monkey visual cortex. Vision Res 23:775–786Google Scholar
  18. Tomko GJ, Crapper DR (1974) Neuronal variability: non-stationary responses to identical visual stimuli. Brain Res 79:405–418Google Scholar

Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • R. Vogels
    • 1
  • W. Spileers
    • 1
  • G. A. Orban
    • 1
  1. 1.Laboratorium voor Neuro- en Psychofysiologie, K.U. LeuvenLeuvenBelgium

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