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Experimental Brain Research

, Volume 77, Issue 2, pp 271–282 | Cite as

Cat red nucleus activity preceding movement depends on initiation conditions

  • J. F. Dormont
  • D. Farin
  • A. Schmied
  • M. Amalric
Article

Summary

The activity of 98 Red Nucleus neurons was recorded in 3 cats operantly conditioned to perform a ballistic forelimb flexion movement triggered after a brief sound in a simple Reaction Time condition, or Delayed after the same sound in the presence of a tone cue. Fifty-eight task related neurons presented changes of activity in either one or both conditions. Forty-four of them were studied quantitatively and classified in 3 categories: 1) only 16% of the units presented similar changes of firing preceding the triggered or delayed movement; 2) most units (55%) presented different changes of activity in the two conditions: in the Delayed condition, the activation occurred earlier before the movement, and/or the change in magnitude was reduced or the pattern of activity was modified; 3) moreover, for 29% of the units, the change of activity observed before movement in the Reaction Time condition was severely reduced or even absent in the Delayed condition. For some of these neurons a building-up of activity was observed very early in the Reaction Time condition, during the preparatory period, well before the occurrence of the conditioned stimulus. These results show that the Red Nucleus activity preceding a movement is clearly dependent on its initiation conditions. The distinct patterns of unit firing observed in the Reaction Time condition and in the Delayed condition are tentatively related to the different preparation and initiation constraints determined by the behavioral conditions.

Key words

Red nucleus Motor initiation Single-unit activity Reaction time Delayed movement Cat 

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References

  1. Amalric M, Condé H, Dormont JF, Schmied A (1983a) Are coding schemes actually used? The cooling test demonstration. In: J Massion, J Paillard, W Schultz, M Wiesendanger (eds) Neural coding of motor performance. Exp Brain Res Suppl 7:204–209Google Scholar
  2. Amalric M, Condé H, Dormont JF, Farin D, Schmied A (1983b) Cat red nucleus changes of activity during the motor initiation in a reaction time task. Exp Brain Res 52:210–218Google Scholar
  3. Blair-Thomas CA, Luschei ES (1975) Increases in reflex excitability of monkey masseter motoneurons before a jaw-bite reaction-time task. J Neurophysiol 38:981–989Google Scholar
  4. Brooks VB (1979) Motor programs revisited. In: RE Talbott, DR Humphrey (eds) Posture and movement. Raven Press, New York, pp 13–49Google Scholar
  5. Brooks VB (1986) Postural control. In: The neural basis of motor control. Oxford Univ Press, pp 160–180Google Scholar
  6. Brunia CHM, Haag SAVM (1986) Preparation for action: slow potentials and EMG. In: H Hener, C Fromm (eds) Generation and modulation of action patterns. Exp Brain Res Series 15:28–40Google Scholar
  7. Carter MC, Shapiro DC (1984) Control of sequential movements: evidence for generalized motor programs. J Neurophysiol 52:787–796Google Scholar
  8. Chapman CE, Spidalieri G, Lamarre Y (1986) Activity of dentate neurons during arm movements triggered by visual, auditory, and somesthetic stimuli in the monkey. J Neurophysiol 55:203–226Google Scholar
  9. Cheney PD, Mewes K, Fetz EE (1988) Encoding of motor parameters by corticomotoneuronal (CM) and rubromotoneuronal (RM) cells producing postspike facilitation of forelimb muscles in the behaving monkey. Behav Brain Res 28:181–191Google Scholar
  10. Condé F, Condé H (1982) The rubro-olivary tract in the cat, as demonstrated with the method of retrograde transport of horseradish peroxidase. Neuroscience 7:715–724Google Scholar
  11. Conrad B, Wiesendanger M, Katsunami K, Brooks VB (1977) Precentral unit activity related to control of arm movements. Exp Brain Res 29:85–95Google Scholar
  12. Conrad B, Benecke R, Goehmann (1983) Premovement silent period in fast movement initiation. Exp Brain Res 51:310–313Google Scholar
  13. Dormont JF, Schmied A, Amalric, M, Farin D (1988) Motor initiation with and without time constraint: unit activity in the cat red nucleus. Eur J Neurosci Suppl 253Google Scholar
  14. Evarts EV, Fromm C, Kröller J, Jennings VA (1983) Motor cortex control of finely graded forces. J Neurophysiol 49:1199–1215Google Scholar
  15. Gemba H, Sasaki K (1984) Distribution of potentials preceding visually initiated and self-paced hand movements in various cortical areas. Brain Res 306:207–214Google Scholar
  16. Ghez C, Kubota K (1977) Activity of red nucleus neurons associated with a skilled forelimb movement in the cat. Brain Res 131:383–388Google Scholar
  17. Gibson AR, Houk JC, Kohlerman NJ (1985a) Magnocellular red nucleus activity during different types of limb movement in the macaque monkey. J Physiol 358:527–549Google Scholar
  18. Gibson AR, Houk JC, Kohlerman NJ (1985b) Relation between red nucleus discharge and movement parameters in trained macaque monkeys. J Physiol 358:551–570Google Scholar
  19. Gray BG, Dostrovsky JO (1984) Red nucleus modulation of somatosensory responses of cat spinal cord dorsal horn neurons. Brain Res 311:171–175Google Scholar
  20. Jasper HH, Ajmone-Marsan C (1954) A stereotaxic atlas of the diencephalon of the cat. Natl Res Council of Canada, OttawaGoogle Scholar
  21. Kurata K, Wise SP (1988a) Premotor cortex of rhesus monkeys: set-related activity during two conditional motor tasks. Exp Brain Res 69:327–343Google Scholar
  22. Kurata K, Wise SP (1988b) Premotor and supplementary motor cortex in rhesus monkeys: neuronal activity during externally-and internally-instructed motor tasks. Exp Brain Res 72:237–248Google Scholar
  23. Lamarre Y, Busby L, Spidalieri G (1983) Fast ballistic arm movements triggered by visual, auditory, and somesthetic stimuli in the monkey. I. Activity of precentral cortical neurons. J Neurophysiol 50:1343–1358Google Scholar
  24. Lecas JC, Requin J, Anger C, Vitton N (1986) Changes in neuronal activity of the monkey precentral cortex during preparation for movement. J Neurophysiol 56:1680–1702Google Scholar
  25. Mann SE, Thau R, Schiller PH (1988) Conditional task-related responses in monkey dorsomedial frontal cortex. Exp Brain Res 69:460–468Google Scholar
  26. Martin JH, Ghez C (1988) Red nucleus and motor cortex: parallel motor systems for the initiation and control of skilled movement. Behav Brain Res 28:217–223Google Scholar
  27. Mauritz KH, Wise SP (1986) Premotor cortex of the rhesus monkey: neuronal activity in anticipation of predictable environmental events. Exp Brain Res 61:229–244Google Scholar
  28. Mellah S, Rispal-Padel L, Rivière G (1988) The effects of motor preparation on the discharge pattern of isolated motor units during a voluntary isotonic movement. Eur J Neurosci Suppl 149Google Scholar
  29. Miles FA, Evarts EV (1979) Concepts of motor organization. Ann Rev Psychol 30:327–362Google Scholar
  30. Nieoullon A, Vuillon-Cacciuttolo G, Dusticier N, Kerkérian L, André D, Bosler O (1988) Putative neurotransmitters in the red nucleus and their involvement in postlesion adaptive mechanisms. Behav Brain Res 28:163–174Google Scholar
  31. Okano K, Tanji J (1987) Neuronal activities in the primate motor fields of the agranular frontal cortex preceding visually triggered and self-paced movement. Exp Brain Res 66:155–166Google Scholar
  32. Passingham RE (1988) Premotor cortex and preparation for movement. Exp Brain Res 70:590–596Google Scholar
  33. Pragay EB, Mirsky AF, Nakamura RK (1987) Attentionrelated unit activity in the frontal association cortex during a go/no-go visual discrimination task. Exp Neurol 96:481–500Google Scholar
  34. Romo R, Schultz W (1987) Neuronal activity preceding selfinitiated or externally timed arm movements in area 6 of monkey cortex. Exp Brain Res 67:656–662Google Scholar
  35. Sawaguchi T (1987) Properties of neuronal activity related to a visual reaction time task in the monkey prefrontal cortex. J Neurophysiol 58:1080–1099Google Scholar
  36. Schmied A, Bénita M, Condé H, Dormont JF (1979) Activity of ventrolateral thalamic neurons in relation to a simple reaction time task in the cat. Exp Brain Res 36:285–300Google Scholar
  37. Schmied A, Amalric M, Dormont JF, Condé H, Farin D (1988) Participation of the red nucleus in motor initiation: unit recording and cooling in cats. Behav Brain Res 28:207–216Google Scholar
  38. Schultz W, Romo R (1988) Neuronal activity in the monkey striatum during the initiation of movements. Exp Brain Res 71:431–436Google Scholar
  39. Smith AM, Hepp-Reymond MC, Wyss UR (1975) Relation of activity in precentral cortical neurons to force and rate of force change during isometric contractions of finger muscles. Exp Brain Res 23:315–332Google Scholar
  40. Sullivan SJ, Hayes KC (1987) Changes in short and long latency stretch reflexes prior to movement initiation. Brain Res 412:139–143Google Scholar
  41. Tanji J, Evarts EV (1976) Anticipatory activity of motor cortex neurons in relation to direction of an intended movement. J. Neurophysiol 39:1062–1068Google Scholar
  42. Wetzel MC (1986) Operant conditioning in motor and neural integration. Neurosci Biobehav Rev 10:387–429Google Scholar
  43. Vicario DS, Martin JH, Ghez C (1983) Specialized subregions in the cat motor cortex: a single unit analysis in the behaving animal. Exp Brain Res 51:351–367Google Scholar
  44. Wise SP (1985) The primate premotor cortex: past, present and preparatory. Ann Rev Neurosci 8:1–19Google Scholar

Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • J. F. Dormont
    • 1
  • D. Farin
    • 1
  • A. Schmied
    • 1
  • M. Amalric
    • 1
  1. 1.Laboratoire de Neurobiologie et Neuropharmacologie du Développement, CNRS URA 1121, Bât 440Université de Paris-SudOrsay CedexFrance

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