Human Genetics

, Volume 56, Issue 3, pp 395–396 | Cite as

Bf polymorphism. A very fast variant from Nigeria

  • B. Larsen
  • L. S. Salimonu
  • C. Gow
  • W. H. Marshall
Original Investigations
Received:

Summary

In a collection of Nigerian serum samples typed for alleles of factor B of the alternative complement pathway, a very high frequency of BfF was found (0.69). In addition, a new variant was found in two samples. This variant (F1.29) moved faster than BfF1. It was hemolytically active.

Keywords

Internal Medicine Serum Sample Metabolic Disease Complement Pathway Fast Variant 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

References

  1. Albert E, Rittner C, Grosse-Wilde H, Netzel B, Scholz S (1975) Recombination frequency and linkage disequilibrium between HL-A and Bf. Munksgaard, Copenhagen, pp 941–944Google Scholar
  2. Allen F (1974) Linkage of HLA and GBG. Vox Sang 27:382–384PubMedGoogle Scholar
  3. Alper A, Boenisch T, Watson L (1972) Genetic polymophism in human glycine-rich beta-glycoprotein. J Exp Med 135: 68–80CrossRefPubMedGoogle Scholar
  4. Hauptmann G, Tongio M, Mayer S (1976) Bf polymorphism: Study of a new variant (F0.55). Hum Genet 33:275–278CrossRefPubMedGoogle Scholar
  5. Hauptmann G, Wertheimer E, Tongio M, Mayer S (1977) Bf polymorphism: Another variant (S00.8). Hum Genet 36:109–111PubMedGoogle Scholar
  6. Larsen B, Arnason A, Barnard J, Buehler S, Edwards J, Marshall WH (1977) Bf types of HLA haplotyped individuals in an isolated Newfoundland population. Tissue Antigens 10:403–409PubMedGoogle Scholar
  7. Mauff G, Gauchil F, Hitzeroth H (1976) Polymorphism of properdin factor B in South African Negroid, Indian and Colored populations. Hum Genet 33:319–322CrossRefPubMedGoogle Scholar
  8. Rittner C, Grosse-Wilde H, Rittner B, Netzel B, Scholz S, Lorenz H, Albert E (1975) Linkage group HL-A-MLC-Bf (properdin factor B). Humangenetik 27:173–183PubMedGoogle Scholar
  9. Scherz R, Pflugshaupt R, Bütler R (1977) Genetic polymorphism of glycine-rich beta-glycoprotein in the Swiss and Italian populations. Hum Hered 27:143–146PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • B. Larsen
    • 1
  • L. S. Salimonu
    • 2
  • C. Gow
    • 1
  • W. H. Marshall
    • 1
  1. 1.Faculty of MedicineMemorial University of NewfoundlandSt. John'sCanada
  2. 2.University College HospitalIbadanNigeria

Personalised recommendations