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Human Genetics

, Volume 77, Issue 2, pp 142–144 | Cite as

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1

  • D. F. Callen
  • E. Baker
  • R. N. Simmers
  • R. Seshadri
  • I. B. Roninson
Original Investigations

Summary

Multiple drug resistance has been shown to be associated with amplification/increased expression of a gene designated MDR. The localization of one member of the MDR gene family, MDR1, to the long arm of chromosome 7 by in situ hybridization is reported.

Keywords

Internal Medicine Gene Family Resistance Gene Drug Resistance Metabolic Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • D. F. Callen
    • 1
  • E. Baker
    • 1
  • R. N. Simmers
    • 1
  • R. Seshadri
    • 2
  • I. B. Roninson
    • 3
  1. 1.Cytogenetics Unit, Department of HistopathologyAdelaide Children's HospitalNorth AdelaideAustralia
  2. 2.Department of HaematologyFlinders Medical CentreBedford ParkAustralia
  3. 3.Center for GeneticsUniversity of Illinois at ChicagoChicagoUSA

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