Molecular and General Genetics MGG

, Volume 132, Issue 1, pp 31–40 | Cite as

Transposition of ampicillin resistance from RP4 to other replicons

  • R. W. Hedges
  • A. E. Jacob


The ampicillin resistance (β-lactamase) determinant of RP4 can be transposed onto various other replicons genetically unrelated to RP4 including several but not all R factors.

Plasmids which acquire this resistance show an increase in molecular weight. They also acquire the ability to transpose the ampicillin resistance to further replicons.


Molecular Weight Ampicillin Ampicillin Resistance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • R. W. Hedges
    • 1
  • A. E. Jacob
    • 1
  1. 1.Bacteriology DepartmentRoyal Postgraduate Medical SchoolLondon

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