Urological Research

, Volume 14, Issue 3, pp 119–122 | Cite as

Oncogenes and malignant transformation

  • H. van Ormondt
  • A. J. van der Eb
Invited Review

Abbreviations

EGF

epidermal growth factor

PDGF

plateletderived growth factor

LTR

long terminal repeat (of retroviral genome)

RSV

Rous sarcoma virus; chr.: chromosome

IgH

immunoglobulin heavy chain

NMU

nitrosomethylurea

DMN

demethylnitrosamine

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Albino AP et al (1984) Transforming ras genes from human melanoma: a manifestation of tumor heterogenicity? Nature 308:69–74Google Scholar
  2. 2.
    Balmain A et al (1984) Activation of the mouse cellular Harvey ras gene in chemically induced benign skin papillomas. Nature 307:658–660Google Scholar
  3. 3.
    Guerrero J et al (1984) A molecular approach to leukemogenesis: Mouse lymphomas contain an activated C-ras oncogene. Proc Natl Acad Sci 81:202–205Google Scholar

The following review articles contain detailed information on the subjects discussed in this paper

  1. 6.
    Bishop JM (1983) Cellular oncogenes and retroviruses. Annu Rev Biochem 52:301–354Google Scholar
  2. 7.
    Varmus HE (1983) The molecular genetics of cellular oncogenes. Annu Rev Genet 18:553–612Google Scholar
  3. 8.
    Weinberg RA (1985) The action of oncogenes in the cytoplasm and nucleus. Science 230:770–776Google Scholar

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • H. van Ormondt
    • 1
  • A. J. van der Eb
    • 1
  1. 1.Sylvius LaboratoriesDepartment of Medical BiochemistryLeidenThe Netherlands

Personalised recommendations