Applied Microbiology and Biotechnology

, Volume 19, Issue 5, pp 316–320 | Cite as

A study on the alkaloid production by resting cell suspensions of Catharanthus roseus in a continuous flow reactor

  • A. Pareilleux
  • R. Vinas


During batch cultivation of Catharanthus roseus cell suspensions, alkaloids were found in the culture medium after growth had ceased. Resting cell suspensions with high alkaloid content were obtained by transferring the cells to a medium devoid of 2.4 D (2.4 dichlorophenoxy-acetic acid). A production system with continuous feeding was developped to study alkaloid production by these resting cell suspensions.


Cell Suspension Alkaloid Production System Batch Cultivation Continuous Flow 
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Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • A. Pareilleux
    • 1
  • R. Vinas
    • 1
  1. 1.Departement de Génie Biochimique et Alimentaire, ERA-CNRS 879Institut National des Sciences AppliquéesToulouse CedexFrance

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