European Journal of Nuclear Medicine

, Volume 3, Issue 2, pp 87–89 | Cite as


A contribution to the study of its structure
  • Ugo Fonda
  • Bente Pedersen


Sephadex column chromatography has shown that 99mTc-diethyl-HIDA consists of two clearly separable components. One of them seems to be an intermediate compound changing into the other, almost completely within two hours after reconstitution of the diethyl-HIDA (Solco HIDA) with pertechnetate. The two components could be the mono- and biscomplex of N-(2,6-diethyl-acetanilid)-imino diacetic acid with one atom of technetium. Animal experiments show that there is no important difference in the biological distribution in mice between the two components.


Public Health Chromatography Animal Experiment Nuclear Medicine Column Chromatography 
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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • Ugo Fonda
    • 1
  • Bente Pedersen
    • 1
  1. 1.The Isotope-PharmacyBrønshøjDenmark

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