Experimental Brain Research

, Volume 27, Issue 5, pp 523–538 | Cite as

Neuronal activity in the vestibular nuclei of the alert monkey during vestibular and optokinetic stimulation

  • W. Waespe
  • V. Henn


Recordings from neurons of the vestibular nuclei were performed in alert monkeys. Type I and type II units were identified by rotating the monkey about a vertical axis. All neurons responded also when only the visual surround was rotated around the stationary monkey. The combination of visual and vestibular stimulation points towards non-algebraic summation characteristics for the two inputs, with each input dominating the response over a certain range.

Key words

Vestibular neurons Optokinetic nystagmus Visual-vestibular interaction Alert monkey 


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  1. Allum, J.H. J., Graf, W., Dichgans, J., Schmidt, C.L.: Visual-vestibular interactions in the vestibular nuclei of the goldfish. Exp. Brain Res. 26, 463–485 (1976)Google Scholar
  2. Angaut, P., Brodal, A.: The projection of the “vestibulo-cerebellum” onto the vestibular nuclei in the cat. Arch. Ital. Biol. 105, 441–479 (1967)Google Scholar
  3. Bond, H.W., Ho, P.: Solid miniature silver-silver chloride electrodes for chronic implantations. Electroenceph. clin. Neurophysiol. 28, 206–208 (1970)Google Scholar
  4. Büttner, U., Henn, V.: Thalamic unit activity in the alert monkey during natural vestibular stimulation. Brain Res. 103, 127–132 (1976)Google Scholar
  5. Dichgans, J., Brandt, Th.: Visual-vestibular interaction and motion perception. In: Cerebral control of eye movements and motion perception (eds. J. Dichgans and E. Bizzi). Bibl. Ophthal. Vol. 82, pp. 327–338 1972Google Scholar
  6. Dichgans, J., Schmidt, C.L., Graf, W.: Visual input improves the speedometer function of the vestibular nuclei in the goldfish. Exp. Brain Res. 18, 319–322 (1973)Google Scholar
  7. Duensing, F., Schaefer, K.P.: Die Aktivität einzelner Neurone im Bereiche der Vestibulariskerne bei Horizontalbeschleunigungen unter besonderer Berücksichtigung des vestibulären Nystagmus. Arch. Psychiatr. Nervenkr. 198, 224–252 (1958)Google Scholar
  8. Fernandez, C., Goldberg, J.M.: Physiology of peripheral neurons innervating semicircular canals of the squirrel monkey. II. Response to sinusoidal stimulation and dynamics of peripheral vestibular system. J. Neurophysiol. 34, 661–675 (1971)Google Scholar
  9. Fuchs, A.F., Kimm, J.: Unit activity in vestibular nucleus of the alert monkey during horizontal angular accelerations and eye movements. J. Neurophysiol. 38, 1140–1161 (1975)Google Scholar
  10. Henn, V., Young, L.R., Finley, C.: Vestibular nucleus units in alert monkeys are also influenced by moving visual fields. Brain Res. 71, 144–149 (1974)Google Scholar
  11. Henn, V., Young, L.R.: Ernst Mach on the vestibular organ 100 years ago. J. Otolaryng. (Basel) 37, 138–148 (1975)Google Scholar
  12. Ito, M., Nisimaru, N., Yamamoto, M.: Specific neuronal connections for the cerebellar control of vestibulo-ocular reflexes. Brain Res. 60, 238–243 (1973)Google Scholar
  13. Keller, E., Daniels, P.: Oculomotor related interaction of vestibular and visual stimulation in vestibular nucleus cells in alert monkey. Exp. Neurol. 46, 187–198 (1975)Google Scholar
  14. Keller, E.L.: Behavior of horizontal semicircular canal afferents in alert monkey during vestibular and optokinetic stimulation. Exp. Brain Res. 24, 459–471 (1976)Google Scholar
  15. Klinke, R., Schmidt, C.L.: Efferent influence on the vestibular organ during active movements of the body. Pflügers Arch. 318, 325–332 (1970)Google Scholar
  16. Koerner, F., Schiller, P.H.: The optokinetic response under open and closed loop conditions in the monkey. Exp. Brain Res. 14, 318–330 (1972)Google Scholar
  17. Komatsuzaki, A., Harris, H.E., Alpert, J., Cohen, B.: Horizontal nystagmus of Rhesus monkeys. Acta oto-laryng. (Stockh.) 67, 535–551 (1969)Google Scholar
  18. Lisberger, S.G., Fuchs, A.F.: Response of flocculus Purkinje cells to adequate vestibular stimulation in the alert monkey: fixation vs. compensatory eye movements. Brain Res. 69, 347–353 (1974)Google Scholar
  19. Mach, E.: Grundlinien der Lehre von den Bewegungsempfindungen. Leipzig: Engelmann, 1875 (reprint Amsterdam: Bonset, 1967)Google Scholar
  20. Maekawa, K., Simpson, J.I.: Climbing fiber activation of Purkinje cells in the flocculus by impulses transferred through the visual pathway. Brain Res. 39, 245–251 (1972)Google Scholar
  21. Melvill Jones, G., Milsum, J.H.: Frequency response analysis of central vestibular unit activity resulting from rotational stimulation of the semicircular canals. J. Physiol. (Lond.) 219, 191–215 (1971)Google Scholar
  22. Miles, F.A.: Single unit firing patterns in the vestibular nuclei related to voluntary eye movements and passive body rotation in conscious monkeys. Brain Res. 71, 215–224 (1974)Google Scholar
  23. Miles, F.A., Fuller, J.H.: Visual tracking and the primate flocculus. Science 189, 1000–1002 (1975)Google Scholar
  24. Miles, T. S., Henn, V. S.: Time constants of secondary vestibular neurons recorded from alert monkeys. Pflügers Arch. Suppl. 362, R49 (1976)Google Scholar
  25. Schneider, L.W., Anderson, D.J.: Transfer characteristics of first and second order lateral canal vestibular neurons in gerbil. Brain Res. 112, 61–76 (1976)Google Scholar
  26. Shimazu, H., Precht, W.J.: Tonic and kinetic responses of cats vestibular neurons to horizontal angular acceleration. J. Neurophysiol. 28, 991–1013 (1965)Google Scholar
  27. Shimazu, H., Precht, W.J.: Inhibition of central vestibular neurons from the contralateral labyrinth and its mediating pathway. J. Neurophysiol. 29, 467–492 (1966)Google Scholar
  28. Takemori, S., Cohen, B.: Loss of visual suppression of vestibular nystagmus after flocculus lesions. Brain Res. 72, 213–224 (1974)Google Scholar

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • W. Waespe
    • 1
  • V. Henn
    • 1
  1. 1.Neurologische KlinikUniversität ZürichZürichSwitzerland

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