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Experimental Brain Research

, Volume 48, Issue 2, pp 309–313 | Cite as

Non-cerebellar visual afferents to the vestibular nuclei involving the prepositus hypoglossal complex: An autoradiographic study in the rat

  • L. Cazin
  • M. Magnin
  • J. Lannou
Research Note

Summary

Radioactive amino-acids were injected into the nucleus reticularis tegmenti pontis (NRTP) and the pretectum (PT) in the rat. Beside the labeling of the several nuclei which are known to receive afferents of either the NRTP and/or the PT, monosynaptic projections from these two structures to the prepositus hypoglossal complex (PHN) were demonstrated. Pretectal visual inputs to the vestibular nuclei (VN) may thus be conveyed not only by the classical PT-inferior olive-cerebellar route, but also by two other non-cerebellar ones involving the strong efferent projections of the PHN onto the VN. These last two pathways are strong candidates to account for the residual visual sensitivity of VN neurons after cerebellectomy or inferior olive lesions.

Key words

Vestibular nuclei Visual afferents 

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References

  1. Cazin L, Precht W, Lannou J (1980a) Pathways mediating optokinetic responses of vestibular nucleus neurons in the rat. Pflügers Arch 384: 19–29Google Scholar
  2. Cazin L, Precht W, Lannou J (1980b) Firing characteristics of neurons mediating optokinetic responses to rat's vestibular neurons. Pflügers Arch 386: 221–230Google Scholar
  3. Cowan WM, Gottbield DI, Hendrickson AE, Price JL, Woolsey TA (1972) The autoradiographic demonstration of axonal connections in the central nervous system. Brain Res 37: 541–551Google Scholar
  4. Graybiel A (1974) Some efferents of the pretectal region in the cat. Anat Rec 178: 365Google Scholar
  5. Gresty M, Baker R (1976) Neurons with visual receptive field, eye movement and neck displacement sensitivity within and around the nucleus prepositus hypoglossi in the alert cat. Exp Brain Res 24: 429–433Google Scholar
  6. Gwyn DG, Nicholson GP, Flumerfelt BA (1977) The inferior olivary nucleus of the rat: a light and electron microscopic study. J Comp Neurol 174: 489–520Google Scholar
  7. Hoddevik GH (1978) The projection from the nucleus reticularis tegmenti pontis onto the cerebellum in the cat. A study using the methods of anterograde degeneration and retrograde axonal transport of horseradish peroxidase. Anat Embryol 153: 227–242Google Scholar
  8. Holstege G, Collewijn H (1980) The efferent connection of the nucleus of the optic tract of the rabbit. Neurosci Lett [Suppl] 5: S183Google Scholar
  9. Keller EL, Precht W (1979) Visual vestibular responses in vestibular nuclear neurons in the intact and cerebellectomized alert cat. Neuroscience 4: 1599–1613Google Scholar
  10. König JFR, Klippel RA (1963) The rat brain: a stereotaxic atlas of the forebrain and lower parts of the brain stem. Williams and Wilkins, Baltimore, pp 1–162Google Scholar
  11. McCrea RA, Baker R, Delgado-Garcia J (1979) Afferent and efferent organization of the prepositus hypoglossi nucleus. Prog Brain Res 50: 653–665Google Scholar
  12. Maekawa K, Takeda T (1978) Origin of mossy fiber projection to the cerebellar flocculus from the optic nerves in rabbits. In: Ito M, Tsukahara N, Kubota K, Yogi K (eds) Integrative control functions of the brain. Elsevier, Amsterdam, pp 93–95Google Scholar
  13. Maekawa K, Takeda T, Kimura M (1981) Neural activity of nucleus reticularis tegmenti pontis. The origin of visual mossy fiber afferents to the cerebellar flocculus of rabbits. Brain Res 210: 17–30Google Scholar
  14. Miyashita Y, Ito M, Jastreboff PJ, Maekawa K, Nagao S (1980) Effect upon eye movements of rabbits induced by severance of mossy fiber visual pathway to the cerebellar flocculus. Brain Res 198: 210–215Google Scholar
  15. Mizuno N, Mochizuki K, Akimoto C, Matsushima R (1973) Pretectal projections to the inferior olive in the rabbit. Exp Neurol 39: 498–506Google Scholar
  16. Pompeiano O, Mergner T, Corvaja N (1978) Commissural, perihypoglossal and reticular afferent projections to the vestibular nuclei in the cat. An experimental anatomical study with the method of the retrograde transport of horseradish peroxidase. Arch Ital Biol 116: 130–172Google Scholar
  17. Precht W, Strata P (1980) On the pathway mediating optokinetic responses in vestibular nuclear neurons. Neuroscience 5: 777–787Google Scholar
  18. Scalia F (1972) The termination of retinal axons in the pretectal region of mammals. J Comp Neurol 145: 223–257Google Scholar
  19. Terasawa K, Otani K, Yamada J (1979) Descending pathways of the nucleus of the optic tract in the rat. Brain Res 173: 405–417Google Scholar
  20. Yamamoto M (1979) Topographical representation in rabbit cerebellar flocculus for various afferent inputs from the brainstem investigated by means of retrograde axonal transport of horseradish peroxidase. Neurosci Lett 12: 29–34Google Scholar

Copyright information

© Springer-Verlag 1982

Authors and Affiliations

  • L. Cazin
    • 1
  • M. Magnin
    • 2
  • J. Lannou
    • 1
  1. 1.Laboratoire de Neurophysiologie SensorielleFaculté des Sciences et des Techniques de RouenMont-Saint-AignanFrance
  2. 2.Laboratoire de Neuropsychologie ExpérimentaleINSERM U.94BronFrance

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