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Experimental Brain Research

, Volume 84, Issue 2, pp 417–425 | Cite as

Medial vestibular nucleus in the guinea-pig

I. Intrinsic membrane properties in brainstem slices
  • M. Serafin
  • C. de Waele
  • A. Khateb
  • P. P. Vidal
  • M. Mühlethaler
Article

Summary

Intracellular recordings were obtained from medial vestibular nuclei neurones (MVNn) in guinea-pig brainstem slices. Two main distinct neuronal classes were encountered. Type A MVNn (32.3%) were characterized by a broad action potential followed by a deep single afterhyperpolarization, a transient A-like rectification, and a single range of firing in response to current injection. Type B MVNn (47.1%), in contrast, were distinguished by the presence of a thin action potential followed first by a fast and then by a delayed and slower afterhyperpolarization. In addition, they displayed a secondary range of firing in their response to current injection. A majority of B MVNn also had either subthreshold plateau potentials or low threshold spike bursts or a combination thereof. A third, non-homogeneous class of cells, could not be fitted into either one of the two main classes (20.6%, type C MVNn).

Key words

Low threshold spike A-like conductance Bursts In vitro Guinea-pig 

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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • M. Serafin
    • 1
  • C. de Waele
    • 2
  • A. Khateb
    • 1
  • P. P. Vidal
    • 2
  • M. Mühlethaler
    • 1
  1. 1.Département de PhysiologieCMUGenève 4Switzerland
  2. 2.Laboratoire de Physiologie Neurosensorielle, CNRSParis Cedex 06France

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