Cell and Tissue Research

, Volume 176, Issue 4, pp 475–492 | Cite as

Membrane-fusions and cytoplasmic bridges in the cells of the developing cerebellum

  • Gopal D. Das


In the developing cerebellum of the neonate rats membranefusions and cytoplasmic bridges between cells were observed. These membrane-fusions were characterized by the presence of loops of membrane and cytoplasmic bridges between the two limits of the membrane-fusions. They were found between Purkinje cells, Purkinje cells and the migratory cells, mitotically potent cells of the external granular layer, and differentiating granule cells of the internal granular layer. The membrane-fusions were found to be a transient developmental phenomenon. Issues pertaining to the universality of membrane-fusions, their significance in the induction for cell differentiation, and the problem of fixation artifacts are discussed.

Key words

Membrane-fusion Cytoplasmic bridges Induction Cell differentiation Cerebellum 


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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Gopal D. Das
    • 1
  1. 1.Department of Biological SciencesPurdue UniversityWest LafayetteUSA

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