Advertisement

Experimental Brain Research

, Volume 83, Issue 3, pp 598–606 | Cite as

Basic determinants for FM responses in the inferior colliculus of rats

  • P. W. F. Poon
  • X. Chen
  • J. C. Hwang
Article

Summary

The response of 835 click-sensitive neurons in the inferior colliculus (IC) to ramp frequency modulated (FM) tones was studied in the anaesthetized rat. More than 70% of the cells were sensitive to the FM sound, and over 25% were “FM specialized”. Systematic variations of the stimulus parameters showed that sweep velocity, sweep range, and intensity of the FM signal were the 3 basic determinants for the unit response. For an“FM specialized” cell, the response pattern to each of the parameters was either monotonic or bell-shaped. The population statistics of response patterns to the FM parameters, including the tuning factors, were generated. A stimulus domain was proposed to represent the“receptive space” of the FM cells.

Key words

Frequency modulation Inferior colliculus Click-sensitive units Receptive space Rat 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Aitkin L (1986) The auditory midbrain. Humana Press, Clifton, New JerseyGoogle Scholar
  2. Aitkin LM, Boyd J (1978) Acoustic input to the lateral pontine nuclei. Hearing Res 1:67–77Google Scholar
  3. Békésy G von (1960) Experiments in hearing. Wever EG, Transl and ed McGraw Hill, New YorkGoogle Scholar
  4. Borg E (1982) Auditory thresholds in rats of different age and strain: a behavioral and electrophysiological study. Hearing Res 8:101–115Google Scholar
  5. Britt R, Starr A (1976) Synaptic events and discharge patterns of cochlear nucleus cells. II. Frequency-modulated tones. J Neurophysiol 39:179–194Google Scholar
  6. Clopton BM, Winfield JA (1973) Tonotopic organization in the inferior colliculus of the rat. Brain Res 56:355–358Google Scholar
  7. Clopton BM, Winfield JA (1974) Unit responses in the inferior colliculus of rat to temporal auditory patterns of tone sweeps and noise bursts. Exp Neurol 42:532–540Google Scholar
  8. Edwards SB, Ginsburgh CL, Henkel CL, Stein BE (1979) Sources of subcortical projections to the superior colliculus in the cat. J Comp Neurol 184:309–330Google Scholar
  9. Erulkar SD, Nelson PG, Bryan JS (1968) Experimental and theoretical approaches to neural processing in the central auditory pathway. In: Neff WD (eds) Contributions to sensory physiology, Vol 3. Academic Press, New York, pp 149–189Google Scholar
  10. Erulkar SD, Butler RA, Gerstein GL (1968) Excitation and inhibition in cochlear nucleus. II. Frequency-modulated tones. J Neurophysiol 31:537–548Google Scholar
  11. Evans EF, Whitfield IC (1964) Responses of cortical neurons to acoustic stimuli varying periodically in frequency. J Physiol 172:52pGoogle Scholar
  12. Hashikawa T, Kawamura K (1983) Retrograde labeling of ascending and descending neurons in the inferior colliculus: a fluorescent double labeling study in the cat. Exp Brain Res 49:457–461Google Scholar
  13. Hind JE, Goldberg JM, Greenwood DD, Rose JE (1963) Some discharge characteristics of single neurons in the inferior colliculus of the cat. II. Timing of the discharges and observations on binaural stimulation. J Neurophysiol 26:321–341Google Scholar
  14. Kay RH (1982) Hearing of modulation in sounds. Physiol Rev 62:894–969Google Scholar
  15. Kelly JB, Masterton B (1979) Auditory sensitivity of the albino rat. J Comp Physiol Psychol 97:930–936Google Scholar
  16. Mendelson JR, Cynader MS (1985) Sensitivity of cat primary auditory cortex (AI) neurons to the direction and rate of frequency modulation. Brain Res 327:331–335Google Scholar
  17. Møller AR (1969) Unit responses in the cochlear nucleus of the rat to sweep tones. Acta Physiol Scand 76:503–512Google Scholar
  18. Møller AR (1971) Unit responses in the rat cochlear nucleus to tones of rapidly varying frequency and amplitude. Acta Physiol Scand 81:540–556Google Scholar
  19. Møller AR (1972) Coding of amplitude and frequency modulated sounds in the cochlear nucleus of the rat. Acta Physiol Scand 86:223–238Google Scholar
  20. Nelson PG, Erulkar SD, Bryan JS (1966) Responses of units of the inferior colliculus to time-varying acoustic stimuli. J Neurophysiol 29:834–860Google Scholar
  21. Phillips DP, Mendelson JR, Cynader MS, Douglas RM (1985) Responses of single neurons in cat auditory cortex to time-varying stimuli: frequency-modulated tones of narrow excursion. Exp Brain Res 58:443–454Google Scholar
  22. Rees A, Møller AR (1983) Responses of neurons in the inferior colliculus of the rat to AM and FM tones. Hearing Res 10:301–330Google Scholar
  23. Rose JE, Greenwood DD, Goldberg JM, Hind, JE (1963) Some discharge characteristics of single neurons in the inferior colliculus of the cat. I. Tonotopical organization, relation of spikecounts to tone intensity, and firing pattern of single elements. J Neurophysiol 26:294–320Google Scholar
  24. Sales GD (1972a) Ultrasound and aggressive behavior in rats and other small mammals. Animal Behav 20:88–100Google Scholar
  25. Sales GD (1972b) Ultrasound and mating behavior in rodents with some observations on other behavioral situations. J Zool 168:149–164Google Scholar
  26. Semple MN, Aitkin LM (1979) Representation of the frequency and lateralaty by units in central nucleus of cat inferior colliculus. J Neurophysiol 42:1626–1639Google Scholar
  27. Sinex DG, Geisler CD (1981) Auditory-nerve fiber responses to frequency-modulated tones. Hearing Res 4:127–148Google Scholar
  28. Suga N (1964) Recovery cycles and responses to frequency modulated tone pulses in auditory neurons of echo-locating bats. J Physiol 175:50–80Google Scholar
  29. Suga N (1965a) Analysis of frequency-modulated sounds by auditory neurons of echo-locating bats. J Physiol 179:26–53Google Scholar
  30. Suga N (1965b) Responses of cortical auditory neurons to frequency modulated sounds in echo-locating bats. Nature 206:890–891Google Scholar
  31. Suga N (1968) Analysis of frequency-modulated and complex sounds by single auditory neurons of bats. J Physiol 198:51–80Google Scholar
  32. Suga N (1969) Classification of inferior collicular neurons of bats in terms of responses to pure tones, FM sounds and noise bursts. J Physiol 200:555–574Google Scholar
  33. Suga N (1984) The extent to which biosonar information is represented in the bat auditory cortex. In: Edelman GM, Gall WE, Cowan WM (eds) Dynamic aspects of neocortical function. John Wiley & Sons, New York, pp 315–373Google Scholar
  34. Syka J, Straschill M (1970) Activation of superior colliculus neurons and motor responses after electrical stimulation of the inferior colliculus. Exp Neurol 28:384–392Google Scholar
  35. Thompson GC, Masterton RB (1978) Brain stem auditory pathways involved in reflexive head orientation to sound. J Neurophysiol 41:1183–1202Google Scholar
  36. Watanabe T, Ohgushi K (1968) FM sensitive auditory neurons. Proc Jpn Acad 44:968–973Google Scholar
  37. Whitfield IC, Evans EF (1965) Responses of auditory cortical neurons to stimuli of changing frequency. J Neurophysiol 28:655–672Google Scholar

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • P. W. F. Poon
    • 1
  • X. Chen
    • 1
  • J. C. Hwang
    • 1
  1. 1.Department of PhysiologyFaculty of Medicine, University of Hong KongHong Kong

Personalised recommendations