Experimental Brain Research

, Volume 80, Issue 1, pp 213–217 | Cite as

Direct visualization of death of neurones projecting to specific targets in the developing rat brain

  • A. R. Harvey
  • D. Robertson
  • K. S. Cole
Research Note
Received:
Accepted:

Summary

The fluorescent dye diamidino yellow was injected into parts of the developing visual and auditory systems in the rat. The dye was retrogradely transported by projecting neurones and was found to stain pyknotic profiles within the labelled cell populations. It is thus possible to visualize directly the death of neurones which project axons to specific and identified target regions within the nervous system.

Key words

Visual system Auditory system Developmental cell death Retrograde transport Diamidino yellow Rat 
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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • A. R. Harvey
    • 1
  • D. Robertson
    • 2
  • K. S. Cole
    • 2
  1. 1.Department of Anatomy and Human BiologyThe University of Western AustraliaNedlands, PerthAustralia
  2. 2.Department of PhysiologyThe University of Western AustraliaNedlands, PerthAustralia

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