Biological Cybernetics

, Volume 68, Issue 3, pp 275–283 | Cite as

A neurophysiologically-based mathematical model of flash visual evoked potentials

  • Ben H. Jansen
  • George Zouridakis
  • Michael E. Brandt
Article

Abstract

Evidence is presented that a neurophysiologically-inspired mathematical model, originally developed for the generation of spontaneous EEG (electroencephalogram) activity, can produce VEP (visual evoked potential)-like waveforms when pulse-like signals serve as input. It was found that the simulated VEP activity was mainly due to intracortical excitatory connections rather than direct thalamic input. Also, the model-generated VEPs exhibited similar relationships between prestimulus EEG characteristics and subsequent VEP morphology, as seen in human data. Specifically, the large correlation between the N1 amplitude and the prestimulus alpha phase angle, and the insensitivity of P2 to the latter feature, as observed in actual VEPs to low intensity flashes, was also found in the model-generated data. These findings provide support for the hypothesis that the spontaneous EEG and the VEP are generated by some of the same neural structures and that the VEP is due to distributed activity, rather than dipolar sources.

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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Ben H. Jansen
    • 1
  • George Zouridakis
    • 1
  • Michael E. Brandt
    • 2
  1. 1.Department of Electrical Engineering and Bioengineering Research CenterUniversity of HoustonHoustonUSA
  2. 2.Department of Psychiatry and Behavioral SciencesUniversity of Texas Medical SchoolHoustonUSA

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