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Cell and Tissue Research

, Volume 150, Issue 2, pp 167–178 | Cite as

Ultrastructural study of pigment cells of human red hair

  • Peter Stanka
Article

Summary

Pigment cells of human red hair (pheomelanocytes) are never connected to keratinocytes by desmosomes or other defined cell junctions. In the dendritic processes of pheomelanocytes, thin filaments, about 50–80 Å in diameter, and microtubuli can be observed. Early prepheomelanosomes contain loosely arranged filaments. With the onset of pheomelanogenesis dense material is deposited on the filaments. Distinction between late prepheomelanosomes and pheomelanosomes is not clearly possible, because of the disorganized appearance of the content. Furthermore, the content of pheomelanosomes sometimes seems to be disintegrated. By means of the DOPA reaction, tyrosinase activity is shown to be present in: a) prepheomelanosomes, b) large cisternae apposed at one side of dictyosomes, c) small cisternae of the smooth endoplasmic reticulum, and d) coated and uncoated vesicles. The results suggest that red pigment granules are formed in a manner similar to that of melanin granules. It is further assumed that an inadequate stability of pheomelanoprotein accounts for the inability of red-haired people to develop effective protection against ultraviolet light.

Key words

Pigment cell Red hair Sunburn Man Electron Microscopy 

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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • Peter Stanka
    • 1
  1. 1.Arbeitsgruppe für Mikromorphologie, Institut für AnatomieRuhr-UniversitätBochum

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