Cancer Immunology, Immunotherapy

, Volume 3, Issue 3, pp 211–213 | Cite as

Comment on the loss of immunogenicity of tumor cells caused by freezing

  • S. P. Leibo
Letter To The Editor
  • 11 Downloads

Keywords

Tumor Cell Cancer Research 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bartlett, G. L., Katsilas, D. C., Kreider, J. W., Purnell, D. M.: Immunogenicity of “viable” tumor cells after storage in liquid nitrogen. Cancer Immunol. Immunother. 2, 127 (1977)Google Scholar
  2. Leibo, S. P.: Fundamental cryobiology of mouse ova and embryos. In: The Freezing of Mammalian Embryos. Ciba Foundation Sympsoium. Elliott, K., Whelan, J. (Eds.). Amsterdam: Elsevier/Excerpta Medica/North Holland 1977, pp. 69–92Google Scholar
  3. Leibo, S. P., Mazur, P.: The role of cooling rates in low temperature preservation. Cryobiology 8, 447 (1971)Google Scholar
  4. Leibo, S. P., Mazur, P.: Methods for the preservation of mammalian embryos by freezing. In: Methods in Mammalian Reproduction. Daniel, J. C., Jr. (Ed.). New York: Academic Press 1977 (in press)Google Scholar
  5. Leibo, S. P., Farrant, J., Mazur, P., Hanna, M. G., Jr., Smith, L. H.: Effects of freezing on marrow stem cell suspensions: interactions of cooling and warming rates in the presence of PVP, sucrose, or glycerol. Cryobiology 6, 315 (1970)Google Scholar
  6. Leibo, S. P., Mazur, P., Jackowski, S. C.: Factors affecting survival of mouse embryos during freezing and thawing. Exp. Cell Res. 89, 79 (1974)Google Scholar
  7. Mazur, P.: Kinetics of water loss from cells at sub-zero temperatures and the likelihood of intracellular freezing. Jour. Gen. Physiol. 47, 347 (1963)Google Scholar
  8. Mazur, P.: Physical and chemical basis of injury in single-celled microorganisms subjected to freezing and thawing. In: Cryobiology. Meryman, H. T. (Ed.). New York: Academic Press 1966Google Scholar
  9. Mazur, P.: Cryobiology: The freezing of biological systems. Science 168, 939 (1970)Google Scholar
  10. Mazur, P., Farrant, J., Leibo, S. P., Chu, E. H. Y.: Survival of hamster tissue culture cells after freezing and thawing. Cryobiology 6, 1 (1969)Google Scholar
  11. Mazur, P., Leibo, S. P., Chu, E. H. Y.: A two-factor hypothesis of freezing injury. Exp. Cell Res. 71, 345 (1972)Google Scholar
  12. Thorpe, P. E., Knight, S. C., Farrant, J.: Optimal conditions for the preservation of mouse lymph node cells in liquid nitrogen using cooling rate techniques. Cryobiology 13, 126 (1976)Google Scholar
  13. Yuhas, J. M., Toya, R. E., Pazmino, N. H.: Neuraminidase and cell viability: failure to detect cytotoxic effects with dye-exclusion techniques. Jour. Nat. Cancer Inst. 53, 465 (1974)Google Scholar

Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • S. P. Leibo
    • 1
  1. 1.Biology DivisionOak Ridge National LaboratoryOak RidgeUSA

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