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Applied Microbiology and Biotechnology

, Volume 39, Issue 4–5, pp 433–437 | Cite as

Optimized nikkomycin production by fed-batch and continuous fermentation

  • Traugott C. Schüz
  • Hans-Peter Fiedler
  • Hans Zähner
Biotechnology

Abstract

We performed fed-batch and continuous fermentations to extend the time of maximal nikkomycin production by Streptomyces tendae Tü 901/S 2566. This was achieved by the fed-batch culture technique. Furthermore, high productivity was obtained at slow growth rates in a continuous fermentation process. Different dilution rates with and without carbon limitation were done and the results were compared.

Keywords

Growth Rate Fermentation Streptomyces Slow Growth Fermentation Process 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Traugott C. Schüz
    • 1
  • Hans-Peter Fiedler
    • 1
  • Hans Zähner
    • 1
  1. 1.Biologisches Institut, LB Mikrobiologie/AntibiotikaUniversität TübingenTübingenGermany

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