Human Genetics

, Volume 87, Issue 2, pp 189–192 | Cite as

The human kininogen gene (KNG) mapped to chromosome 3q26-qter by analysis of somatic cell hybrids using the polymerase chain reaction

  • Dunne Fong
  • David I. Smith
  • Wang-Ting Hsieh
Original Investigations


Kinins, peptide products of kininogens, may be involved in hypertensive and diabetic diseases, and inflammatory disorders. The human kininogen gene (KNG) has been mapped to chromosome 3, using a panel of human-hamster somatic cell hybrids by polymerase chain reaction of hybrid DNA with gene-specific primers. KNG was further assigned to 3q26-3qter, using DNA from a second panel of chromosome 3 deletion mapping cell hybrids.


Peptide Polymerase Chain Reaction Internal Medicine Metabolic Disease Somatic Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • Dunne Fong
    • 1
  • David I. Smith
    • 2
  • Wang-Ting Hsieh
    • 3
  1. 1.Department of Biological Sciences and Bureau of Biological Research, Rutgers, The State University of New JerseyC226 Nelson Biological LaboratoriesPiscatawayUSA
  2. 2.Department of Molecular Biology and GeneticsWayne State University School of MedicineDetroitUSA
  3. 3.Clinical Neurogenetics BranchNational Institute of Mental HealthBethesdaUSA

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