Human Genetics

, Volume 94, Issue 2, pp 207–209

Deletion polymorphism in the gene for angiotensin converting enzyme is associated with elevated fasting blood glucose levels

  • Adriana Zingone
  • Andrea Dominijanni
  • Evelina Mele
  • Onorina Marasco
  • Franca Melina
  • Pasquale Minchella
  • Barbara Quaresima
  • Maria Teresa Tiano
  • Agostino Gnasso
  • Arturo Pujia
  • Nicola Perrotti
Short Communication

DOI: 10.1007/BF00202873

Cite this article as:
Zingone, A., Dominijanni, A., Mele, E. et al. Hum Genet (1994) 94: 207. doi:10.1007/BF00202873

Abstract

The frequency and distribution of angiotensin converting enzyme insertion/deletion (ACE I/D) polymorphism, and its association with other known risk factors for coronary atherosclerosis, has been studied, in a normal south Italian population. Subjects homozygous for deletion showed elevated fasting blood glucose levels when compared with subjects homozygous for insertion. The difference was consistent with an increased number of type 2 diabetics among the former group of subjects.

Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • Adriana Zingone
    • 1
  • Andrea Dominijanni
    • 1
  • Evelina Mele
    • 1
  • Onorina Marasco
    • 1
  • Franca Melina
    • 1
  • Pasquale Minchella
    • 1
  • Barbara Quaresima
    • 1
  • Maria Teresa Tiano
    • 1
  • Agostino Gnasso
    • 1
  • Arturo Pujia
    • 1
  • Nicola Perrotti
    • 1
  1. 1.Dipartimento di Medicina Sperimentale e Clinica c/o Facoltà di Medicina e Chirurgia a CatanzaroUniversità degli Studi di Reggio CalabriaCatanzaroItaly

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