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Springer Seminars in Immunopathology

, Volume 7, Issue 4, pp 387–413 | Cite as

Cytokines and other mediators in rheumatoid arthritis

  • Jean-Michel Dayer
  • Stephen Demczuk
Article

Keywords

Rheumatoid Arthritis Arthritis Internal Medicine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Altman A, Theophilipoulos AN, Weiner R, Katz DH, Dixon FJ (1981) Analysis of T cell function in autoimmune murine strains. Defects in production of and responsiveness to interleukin 2. J Exp Med 154: 791Google Scholar
  2. 2.
    Amento EP, Kurnick JT, Epstein A, Krane SM (1982) Modulation of synovial cell products by a factor from a human cell line: T lymphocyte induction of a mononuclear cell factor. Proc Natl Acad Sci USA 79: 5307Google Scholar
  3. 3.
    Amento EP, Bhalla AK, Kurnick JT, Kradin RL, Clemens TL, Holick SA, Holick MF, Krane SM (1984) 1 α, 25-dihydroxyvitamin D3 induces maturation of the human monocyte cell line U937, and, in association with a factor from human T lymphocytes, augments production of the monokine, mononuclear cell factor. J Clin Invest 73: 731Google Scholar
  4. 4.
    Amento EP, Bhan AK, Krane SM (1984) Effects of interferon γ and mononuclear cell factor on adherent rheumatoid synovial cells: Alterations of Ia expression and collagen synthesis. Arthritis Rheum 27: S 23Google Scholar
  5. 5.
    Anderson CL (1982) Isolation of the receptor IgG from a human monocyte cell line (U937) and from human peripheral blood monocytes. J Exp Med 156: 1947Google Scholar
  6. 6.
    Andreis M, Hurd ER (1977) Macrophage migration inhibitory factor in rheumatoid pericarditis. Arthritis Rheum 20: 969Google Scholar
  7. 7.
    Baker DG, Dayer JM, Roelke M, Schumacher HR, Krane SM (1983) Rheumatoid synovial cell morphologic changes induced by a mononuclear cell factor in culture. Arthritis Rheum 26: 8Google Scholar
  8. 8.
    Barrett AJ (1981) Which proteinases degrade cartilage matrix. Semin Arthritis Rheum 11: 52Google Scholar
  9. 9.
    Baum BJ, Moss J, Breul SD, Crystal RG (1978) Association in normal human fibroblasts of elevated levels of adenosine 3′: 5′-monophosphate with a selective decrease in collagen synthesis. J Biol Chem 253: 3391Google Scholar
  10. 10.
    Beaven MA (1976) Histamine. N Engl J Med 294: 30Google Scholar
  11. 11.
    Berg RA, Moss J, Baum BJ, Crystal RG (1981) Regulation of collagen production by the β-adrenergic system. J Clin Invest 67: 1457Google Scholar
  12. 12.
    Biswas C, Dayer JM (1979) Stimulation of collagenase production by collagen in mammalian cell cultures. Cell 18: 1035Google Scholar
  13. 13.
    Bleackley RC, Horak, H, McElhaney JM, Havele C, Shaw ARE, Turner AR, Paetkau VH (1983) Translation of lymphocyte mRNA for mouse colony stimulating factor. Nucleic Acids Res 11:3027Google Scholar
  14. 14.
    Brinckerhoff CE, McMillan RM, Dayer JM, Harris ED Jr (1980) Inhibition by retinoic acid of collagenase production in rheumatoid synovial cells. N Engl J Med 303: 432Google Scholar
  15. 15.
    Brown RA, Weiss JB, Tomlinson IW, Phillips P, Kumar S (1980) Angiogenic factor from synovial fluid resembling that from tumors. Lancet 2: 682Google Scholar
  16. 16.
    Burmester GR, Yu DTY, Irani AM, Kunkel HG, Winchester RJ (1981) Ia + T cells in synovialfluid and tissues of patients with rheumatoid arthritis. Arthritis Rheum 24: 1370Google Scholar
  17. 17.
    Burmester GR, Dimitriu-Bona A, Waters SJ, Winchester RJ (1983) Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macrophages and fibroblasts. Scand J Immunol 17: 69Google Scholar
  18. 18.
    Canalis E (1983) Effect of hormones and growth factors on alkaline phosphatase activity and collagen synthesis in cultured rat calvariae. Metabolism 32: 14Google Scholar
  19. 19.
    Castor CW, Ritchie JC, Williams CH Jr, Scott ME, Whitney SL, Myers SL, Sloan TB, Anderson BE (1979) Connective tissue activation. XIV. Composition and actions of a human platelet autacoid mediator. Arthritis Rheum 22: 260Google Scholar
  20. 20.
    Cesario TC, Andrews BS, Martin DA, Jason M, Treadwell T, Friou G, Tilles JG (1983) Interferons in synovial fluid and serum of patients with rheumatic diseases. J Rheumatol 10: 647Google Scholar
  21. 21.
    Chattopadhyay H, Chattopadhyay C, Natvig JB, Mellbye OJ, Pahle J (1980) Spontaneous release of leucocyte migration-inhibitory factor by mononuclear cells eluted from rheumatoid synovial tissue. Scand J Immunol 12: 475Google Scholar
  22. 22.
    Chouaib S, Chatenoud L, Klatzmann D, Fradelizi D (1984) The mechanisms of inhibition of human IL 2 production. II. PGE2 induction of suppressor T lymphocytes. J Immunol 132: 1324Google Scholar
  23. 23.
    Geiger C, Vischer TL (1976) Migration inhibition factor-lik activity in inflammatory synovial fluids might be due to proteases. Clin Exp Immunol 26: 176Google Scholar
  24. 24.
    Chung DW, Rixon MW, Que BG, Davie EW (1983) Cloning of fibrinogen genes and their cDNA. Ann NY Acad Sci 408: 449Google Scholar
  25. 25.
    Crabtree GR, Kant JA, Fornace AJ Jr, Rauch CA, Fowlkes DM (1983) Regulation and characterization of the mRNAs for the Aα, Bβ and γ chains of fibrinogen. Ann NY Acad Sci 408: 457Google Scholar
  26. 26.
    Crisp AJ, Chapman CM, Kirkham SE, Schiller AL, Krane SM (1984) (to be published) Articular mastocytosis in rheumatoid arthritis. Arthritis RheumGoogle Scholar
  27. 27.
    Cruchaud A, Despont JP, Roth A, Dayer JM (1984) (to be published) Functions of human monocytes in systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Diagnostic ImmunologyGoogle Scholar
  28. 28.
    Crystal RG, Bitterman PB, Rennard SI, Hance AJ, Keogh BA (1984) Interstitial lung diseases of unknown cause: disorders characterized by chronic inflammation of the lower respiratory tract. N Engl J Med 310: 154, 235Google Scholar
  29. 29.
    Dahlan SE, Bjork J, Hedqvist P, Arfors KE, Hammarstrom S, Lindgren JA, Samuelson B (1981) Leukotrienes promote plasma leakage and leucocyte adhesion in postcapillary venules: In vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci USA 78: 3887Google Scholar
  30. 30.
    Daireaux M, Penfornis H, Langris M, Bocquet J, Pujol JP, Beliard R, Loyau G (1981) Effect of a mononuclear cell culture medium on collagen and glycosaminoglycan production by synovial cells in culture. FEBS Lett 132: 93Google Scholar
  31. 31.
    Dalldorf FG, Cromartie WJ, Anderle SK, Clark RL, Schwab JH (1980) The relation of experimental arthritis to the distribution of streptococcal cell wall fragments. Am J Pathol 100: 383Google Scholar
  32. 32.
    Dayer JM (1982) Effects of retinoids on prostaglandin E2 (PGE2) and mononuclear cell factor (MCF) production by human monocyte cultures. Clin Res 30: 469AGoogle Scholar
  33. 33.
    Dayer JM (1984) (to be published) Monokines and connective tissue destruction in rheumatoid arthritis. In: Lambert PH, Perrin L, Izui S (eds) Proceedings of the workshop on recent advances on systemic lupus erythematosus. Academic Press, New YorkGoogle Scholar
  34. 34.
    Dayer JM, Krane SM (1978) The interaction of immunocompetent cells and chronic inflammation as exemplified by rheumatoid arthritis. Clin Rheum Dis 4: 517Google Scholar
  35. 35.
    Dayer JM, Krane SM, Russell RGG, Robinson DR (1976) Production of collagenase and prostaglandins by isolated adherent rheumatoid synovial cells. Proc Natl Acad Sci USA 73: 945Google Scholar
  36. 36.
    Dayer JM, Robinson DR, Krane SM (1977) Action on anti-inflammatory drugs on synovium. In: Gordon JL, Hazleman BL (eds) Rheumatoid Arthritis. Elsevier North-Holland Biochemical Press, Amsterdam, p 117Google Scholar
  37. 37.
    Dayer JM, Bréard J, Chess L, Krane SM (1979) Participation of monocyte-macrophages and lymphocytes in the production of a factor that stimulates collagenase and prostaglandin release by rheumatoid synovial cells. J Clin Invest 64: 1386Google Scholar
  38. 38.
    Dayer JM, Goldring SR, Robinson DR, Krane SM (1979) Effects of human mononuclear cell factor on cultured rheumatoid synovial cells. Interactions of prostaglandin E2 and cyclic adenosine 3',5'-monophosphate. Biochim Biophys Acta 586: 87Google Scholar
  39. 39.
    Dayer JM, Byrne MH, Krane SM (1980) Effects of a mononuclear cell factor (MCF), indomethacin and prostaglandin E2 (PGE2) on collagen and fibronectin synthesis by cultured rheumatoid synovial cells. Clin Res 28: 343AGoogle Scholar
  40. 40.
    Dayer JM, Goldring SR, Robinson DR, Krane SM (1980) Cell-cell interactions and collagenase production. In: Woolley DE, Evanson JM (eds) Collagenase in normal and pathological connective tissues. John Wiley and Sons, Ltd, England, p 83Google Scholar
  41. 41.
    Dayer JM, Passwell JH, Schneeberger EE, Krane SM (1980) Interactions among rheumatoid synovial cells and monocyte-macrophages: production of collagenase-stimulating factor by human monocytes exposed to concanavalin A or immunoglobulin Fc fragments. J Immunol 124: 1712Google Scholar
  42. 42.
    Dayer JM, Trentham DE, Krane SM (1982) Collagens act as ligands to stimulate human monocytes to produce mononuclear cell factor (MCF) and prostaglandins (PGE2). Collagen Rel Res 2: 523Google Scholar
  43. 43.
    Dayer JM, Zavadil-Grob C, Ucla C, Mach B (1984) (to be published) Translation of mRNA into biological active mononuclear cell factor (≃ interleukin-1) which stimulates prostaglandin E2 and collagenase production by synovial cells. Eur J ImmunologyGoogle Scholar
  44. 44.
    Dayer JM, Roelke MS, Krane SM (1984) (to be published) Effects of prostaglandin E2, trifluoperazine and drugs affecting the cytoskeleton on collagenase production by cultured adherent rheumatoid synovial cells. Biochem PharmacolGoogle Scholar
  45. 45.
    Devos R, Cheroutre H, Taya Y, Degrave W, van Heuverswyn H, Fiers W (1982) Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells. Nucleic Acids Res 10: 2487Google Scholar
  46. 46.
    Devos R, Plaetinck G, Cheroutre H, Simons G, Degrave W, Tavernier J, Remaut E, Fiers W (1983) Molecular cloning of human interleukin 2 cDNA and its expression in E. coli. Nucleic Acids Res 11: 4307Google Scholar
  47. 47.
    Dinarello CA (1984) Interleukin-1. Rev Infect Dis 6: 51Google Scholar
  48. 48.
    Duke O, Panayi GS, Janossy G, Poulter LW, Tidman N (1983) Analysis of T cell subsets in the peripheral blood and synovial fluid of patients with rheumatoid arthritis by mean of monoclonal antibodies. Ann Rheum Dis 42: 357Google Scholar
  49. 49.
    Dyerberg J, Bang HO, Stoffersen E, Moncada S, Vane JR (1978) Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis. Lancet 2: 117Google Scholar
  50. 50.
    Edlund T, Ny T, Ranby M, Heden LO, Palm G, Holmgren E, Josephson S (1983) Isolation of cDNA sequences coding for a part of human tissue plasminogen activator. Proc Natl Acad Sci USA 80: 349Google Scholar
  51. 51.
    Efrat S, Pilo S, Kaempfer R (1982) Kinetics of induction and molecular size of mRNAs encoding human interleukin 2 and γ-interferon. Nature 297: 236Google Scholar
  52. 52.
    Egeland T, Mellbye OJ, Pahle JA (1981) Inflammatory synovial tissue mononuclear cells release leucocyte migration inhibition factor in antigen- and mitogen-free cultures. Ann Rheum Dis 40: 388Google Scholar
  53. 53.
    Egeland T, Lea T, Mellbye OJ (1983) T-cell immunoregulatory functions in rheumatoid arthritis patients. Scand J Immunol 18: 355Google Scholar
  54. 54.
    Elias JA, Rossman MD, Daniele RP (1982) Inhibition of human lung fibroblast growth by mononuclear cells. Am Rev Respir Dis 125: 701Google Scholar
  55. 55.
    Evêquoz V, Bettens F, Kristensen F, Trechsel U, Stadler BM, Dayer JM, Walz A, de Weck AL, Fleisch H (1984) (to be published) Stimulation of rabbit chondrocyte collagenase and prostaglandin E2 production by interleukin 1. Eur J ImmunolGoogle Scholar
  56. 56.
    Fey G, Domdey H, Wiebauer K, Whitehead AS, Odink K (1983) Structure and expression of the C3 gene. Springer Semin Immunopathol 6: 119Google Scholar
  57. 57.
    Fischer S, Weber PC (1984) Prostaglandin I3 is formed in vivo in man after dietary eicosapentaenoic acid. Nature 307: 165Google Scholar
  58. 58.
    Flower RJ, Blackwell GJ (1979) Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which presents prostaglandin generation. Nature 278: 456Google Scholar
  59. 59.
    Folkman J, Haudenschild C (1980) Angiogenesis in vitro. Nature 288: 551Google Scholar
  60. 60.
    Fontana A, Hengartner H, Weber E, Fehr K, Grob PJ, Cohen G (1982) Interleukin 1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol Int 2: 49Google Scholar
  61. 61.
    Foon KA, Wahl SM, Oppenheim JJ, Rosenstreich DL (1976) Serotonin-induced production of a monocyte chemotactic factor by human peripheral blood leukocytes. J. Immunol 117: 1545Google Scholar
  62. 62.
    Ford-Hutchinson AW, Bray MA, Doig MV, Shipley ME, Smith MJH (1980) Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 286: 264Google Scholar
  63. 63.
    Freemont AJ, Jones CJP, Browley M, Andrews D (1983) Changes in vascular endothelium related to lymphocyte collections in diseased synovia. Arthritis Rheum 26: 1427Google Scholar
  64. 64.
    Fuller GM, Ritchie DG (1982) A regulatory pathway for fibrinogen biosynthesis involving an indirect feedback loop. Ann NY Acad Sci 389: 308Google Scholar
  65. 65.
    Fuller GM, Nickerson JM, Adams MA (1983) Translational and cotranslational events in fibrinogen synthesis. Ann NY Acad Sci 408: 440Google Scholar
  66. 66.
    Fung MC, Hapel AJ, Ymer S, Cohen DR, Johnson RM, Campbell HD, Young IG (1984) Molecular cloning of cDNA for murine interleukin-3. Nature 307: 233PubMedGoogle Scholar
  67. 67.
    Gatenby PA, Engelman EG (1981) Immunoregulation of the synovium of rheumatoid arthritis. Lancet 1: 1348Google Scholar
  68. 68.
    Gemsa D (1981) Stimulation of prostaglandin E release from macrophages and possible role in the immune response. Lymphokines 4: 335Google Scholar
  69. 69.
    Goetzl EJ, Kaplan AP (1983) Lipid and peptide mediators of inflammation. Fed Proc 42: 3119Google Scholar
  70. 70.
    Goldberg RL, Parrott DP, Kaplan SR, Fuller GC (1980) Effect of gold sodium thiomalate on proliferation of human rheumatoid synovial cells and on collagen synthesis in tissue culture. Biochem Pharmacol 29: 869Google Scholar
  71. 71.
    Goldring SR, Dayer JM, Krane SM (1984) Rheumatoid synovial cell hormone responses modulated by cell-cell interactions. Inflammation 8: 107Google Scholar
  72. 72.
    Goldstein RH, Polgar P (1982) The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts. J Biol Chem 257: 8630Google Scholar
  73. 73.
    Goodwin JS, Ceuppens J (1983) Regulation of the immune response by prostaglandins. J Clin Immunol 3: 295Google Scholar
  74. 74.
    Goodwin JS, Ceuppens JL, Rodriguez MA (1983) Administration of non-steroidal anti-inflammatory agents in patients with rheumatoid arthritis. JAMA 250: 2485Google Scholar
  75. 75.
    Gowen M, Wood DD, Ihrie EJ, McGuire MKB, Russell RGG (1983) An interleukin 1 like factor stimulates bone resorption in vitro. Nature 306: 375Google Scholar
  76. 76.
    Gray PW, Goeddel DV (1982) Structure of the human immune interferon gene. Nature 298: 859Google Scholar
  77. 77.
    Gray PW, Leung DW, Pennica D, Yelverton E, Najarian R, Simonsen CC, Deranck R, Sherwood PJ, Wallace DM, Berger SL, Levinson AD, Goeddel DV (1982) Expression of human immune interferon cDNA in E. coli and monkey cells. Nature 295: 503Google Scholar
  78. 78.
    Gray A, Dull TJ, Ullrich A (1983) Nucleotide sequence of epidermal growth factor cDNA predicts a 128 000-molecular weight protein precursor. Nature 303: 725Google Scholar
  79. 79.
    Hamerman D, Stephens M, Barland P (1961) Comparative histology and metabolism of synovial tissue in normal and arthritic joints. In: Mills LC, Moyer JH (eds) Inflammation and diseases of connective tissue. Saunders, New York, p 158Google Scholar
  80. 80.
    Hamilton JA, Zabriskie JB, Lachman LB, Chen YS (1982) Streptococcal cell walls and synovial cell activation. Stimulation of synovial fibroblast plasminogen activator activity by monocytes treated with group A streptococcal cell wall sonicates and muramyl dipeptide. J Exp Med 155: 1702Google Scholar
  81. 81.
    Harris ED Jr (1981) Pathogenesis of rheumatoid arthritis. In: Kelley WN, Harris ED Jr, Ruddy S, Sledge CB (eds) Textbook of Rheumatology. Saunders, Philadelphia, p 896Google Scholar
  82. 82.
    Hartung HP, Hadding U (1983) Synthesis of complement by macrophages and modulation of their functions through complement activation. Springer Semin Immunopathol 6: 283Google Scholar
  83. 83.
    Hashida R, Terato K, Miyamoto K, Morimoto T, Hori H, Nagai Y (1982) Effect of polymorphonuclear leukocytes on synovial cell collagenase production. Biomedical Res 3: 506Google Scholar
  84. 84.
    Hasler F, Bluestein HG, Zvaifler NJ, Epstein LB (1983) Analysis of the defects responsible for the impaired regulation of Epstein-Barr virus-induced B cell proliferation by rheumatoid arthritis lymphocytes. I. Diminished gamma interferon production in response to autologous stimulation. J Exp Med 157: 173Google Scholar
  85. 85.
    Hasler F, Bluestein HG, Zvaifler NJ, Epstein LB (1983) Analysis of the defects responsible for the impaired regulation of EBV-induced B cell proliferation by rheumatoid arthritis lymphocytes. II Role of monocytes and the increased sensitivity of rheumatoid arthritis lymphocytes to prostaglandin E. J Immunol 131: 768Google Scholar
  86. 86.
    Hattori T, Hoffman T, Hirata F (1983) Differentiation of a histiocytic lymphome cell line by lipomodulin, a phospholipase inhibitory protein. Biochem Biophys Res Commun 111: 551Google Scholar
  87. 87.
    Hazelton RA (1984) A study of lymphocytotoxins in the sera of families of patients with rheumatoid disease. Arthritis Rheum 27: 233Google Scholar
  88. 88.
    Heppleston AG, Stylls JA (1967) Activity of a macrophage factor in collagen formation by silica. Nature 214: 521Google Scholar
  89. 89.
    Hirano H, Yamada Y, Sullivan M, de Crombrugghe B, Pastan I, Yamada KM (1983) Isolation of genomic DNA clones spanning the entire fibronectin gene. Proc Natl Acad Sci USA 80: 46Google Scholar
  90. 90.
    Hirata F, Iwata M (1983) Role of lipomodulin, a phospholipase inhibitory protein, in immunoregulation by thymocytes. J Immunol 130: 1930Google Scholar
  91. 91.
    Hirata F, Schiffman E, Venkatasu-Bramanian K, Salomon D, Axelrod J (1980) A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids. Proc Natl Acad Sci USA 73: 1720Google Scholar
  92. 92.
    Hirata F, del Carmine R, Nelson CA, Axelrod J, Schiffmann E, Warabi A, De Blas AL, Nirenberg M, Manganiello V, Vaughan M, Kumagai S, Green I, Decker JL, Steinberg AD (1981) Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases. Proc Natl Acad Sci USA 78: 3190Google Scholar
  93. 93.
    Hooks JJ, Jordan GW, Cupps T, Moutsopoulos HM, Fauci AS, Notkins AL (1982) Multiple interferons in the circulation of patients with systemic lupus erythematosus and vasculitis. Arthritis Rheum 25: 396Google Scholar
  94. 94.
    Hsueh W, Desai V, Gonzalez-Crussi F, Lamb R, Chu A (1981) Two phospholipase pool for prostaglandin synthesis in macrophages. Nature 290: 710Google Scholar
  95. 95.
    Ihle JN, Keller J, Oroszlan S, Henderson LE, Copeland TD, Fitch F, Prystowsky MB, Goldwasser E, Schrader JW, Palaszynski E, Dy M, Lebel B (1983) Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity. J Immunol 131: 282Google Scholar
  96. 96.
    Ishikawa H, Ziff M (1976) Electron microscopic observations of immunoreactive cells in the rheumatoid synovial membrane. Arthritis Rheum 19: 1Google Scholar
  97. 97.
    Jalkanen M, Penttinen R (1982) Enhanced fibroblast collagen production by a macrophage-derived factor (CEMF). Biochem Biophys Res Commun 108: 447Google Scholar
  98. 98.
    Jalkanen M, Peltonen J, Kulonen E (1979) Isoelectric focusing of macrophage culture media and the effect of the fractions on the synthesis of DNA and collagen by fibroblasts. Acta Pathol Microbiol Scand Sect [C] 87: 347Google Scholar
  99. 99.
    Janossy G, Duke O, Poulter LW, Panayi G, Bofill M, Goldstein G (1981) Rheumatoid arthritis: a disease of T lymphocyte/macrophage immunoregulation. Lancet 2: 839Google Scholar
  100. 100.
    Jasin HE (1983) Factors controlling articulare cartilage degradation by activation of chondrocytes. In: Weissman G (ed) Advances in inflammation research, vol 5. Raven Press, p 87Google Scholar
  101. 101.
    Jimenez SA, McArthur W, Rosenbloom J (1979) Inhibition of collagen synthesis by mononuclear cell supernates. J Exp Med 150: 1421Google Scholar
  102. 102.
    Johnson RL, Ziff M (1976) Lymphokine stimulation of collagen accumulation. J Clin Invest 58: 240Google Scholar
  103. 103.
    Kampschmidt RF, Upchurch HF, Pulliam LA (1982) Charachterization of a leukocyte-derived endogenous mediator responsible for increased plasma fibrinogen. Ann NY Acad Sci 389: 338Google Scholar
  104. 104.
    Kaplan AP, Silverberg M, Dunn JT, Ghebrehiwet B (1982) Interaction of the clotting, kinin-forming, complement and fibrinolytic pathways in inflammation. Ann NY Acad Sci 389: 25Google Scholar
  105. 105.
    Kaufman JF, Auffray C, Korman AJ, Shackelford DA, Strominger J (1984) The class II molecules of the human and murine major histocompatibility complex. Cell 36: 1Google Scholar
  106. 106.
    Kelley VE, Winkelstein A, Izui S, Dixon FJ (1981) Prostaglandin E1 inhibits T-cell proliferation and renal disease in MRL/1 mice. Clin Immunol Immunopathol 21: 190Google Scholar
  107. 107.
    Kidd VJ, Wallace RB, Itakura K, Woo SLC (1983) α1-antitrypsin deficiency detection by direct analysis of the mutation in the gene. Nature 304: 230Google Scholar
  108. 108.
    Konttinen YT, Reitamo S, Ranki A, Häyry P, Kankaanapää U, Wegelius O (1981) Characterization of the immunocompetent cells of rheumatoid synovium from tissue sections and eluates. Arthritis Rheum 24: 71Google Scholar
  109. 109.
    Krane SM (1981) Aspects of the cell biology of the rheumatoid synovial lesion. Ann Rheum Dis 40: 433Google Scholar
  110. 110.
    Krane SM, Goldring SR, Dayer JM: (1982) Interactions among lymphocytes, monocytes and other synovial cells in the rheumatoid synovium. Lymphokines 7: 75Google Scholar
  111. 111.
    Kuehl FA Jr, Egan RW (1980) Prostaglandins, arachidonic acid, and inflammation. Science 210: 278Google Scholar
  112. 112.
    Kulka JP, Bocking D, Ropes MW, Bauer W (1955) Early joint lesions of rheumatoid arthritis. Arch Pathol 59: 129Google Scholar
  113. 113.
    Kunkel SL, Ogawa H, Conran PB, Ward PA, Zurier RB (1981) Suppression of acute and chronic inflammation by orally administred prostaglandins. Arthritis Rheum 24: 1151Google Scholar
  114. 114.
    Lachman LB, Maizel AL (1983) The interleukins: immunoregulatory molecules. Clin Immunol Newsletter 4: 113Google Scholar
  115. 115.
    Lewis RA, Austen KF (1981) Mediation of local homeostasis and inflammation by leukotrienes and other mast cell-dependent compounds. Nature 293: 103Google Scholar
  116. 116.
    Linker-Israeli M, Bakke AC, Kitridou RC, Gendler S, Gillis S, Horwitz DA (1983) Defective production of interleukin 1 and interleukin 2 in patients with systemic lupus erythematosus (SLE). J Immunol 130: 2651Google Scholar
  117. 117.
    Lusis AJ, Golde DW, Quon DH, Lasky LA (1982) Translation of mRNA for human granulocyte-macrophage colony stimulating factor. Nature 298: 75Google Scholar
  118. 118.
    Maeda S, Nishino N, Obaru K, Mita S, Nomiyama H, Shimada K, Fujimoto K, Teranishi T, Hirano T, Onoue K (1983) Cloning of interleukin 2 mRNAs from human tonsils. Biochim Biophys Res Commun 115: 1040Google Scholar
  119. 119.
    Mainardi CL, Hasty DL, Seyer JM, Kang AH (1980) Specific cleavage of human type III collagen by human polymorphonuclear leukocyte elastase. J Biol Chem 255: 12006Google Scholar
  120. 120.
    McArthur W, Derr K, Dixon M, Jimentz SA, Rosenbloom J (1982) Immune modulation of connective tissue functions: studies on the production of collagen synthesis inhibitory factor by populations of human peripheral blood mononuclear cells. Cell Immunol 74: 126Google Scholar
  121. 121.
    McCord JM (1974) Free radicals and inflammation: protection of synovial fluid by superoxide dismutase. Science 185: 529Google Scholar
  122. 122.
    McLeish KR, Gohara AF, Stelzer GT, Wallace JH (1983) Treatment of murine immune complex glomerulonephritis with prostaglandin E2: Dose-response of immune complex deposition, antibody synthesis, and glomerular damage. Clin Immunol Immunopathol 26: 18Google Scholar
  123. 123.
    Meats JE, McGuire HB, Russell RGG (1980) Human synovium releases a factor which stimulates chondrocyte production of PGE and plasminogen activator. Nature 286: 981Google Scholar
  124. 124.
    Mizel SB (1982) Regulation of immune and inflammatory responses by interleukin 1. Clin Immunol Newsletter 3: 123Google Scholar
  125. 125.
    Mizel SB, Dayer JM, Krane SM, Mergenhagen SE (1981) Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1). Proc Natl Acad Sci USA 78: 2474Google Scholar
  126. 126.
    Moore RN, Hoffeld JT, Farrer JJ, Shadduck RK (1981) Role of colony stimulating factors as primary regulators of macrophage functions. In: Pick E (ed) Lymphokines, vol 3, Academic Press, New York, p 119Google Scholar
  127. 127.
    Morley J (1981) Role of prostaglandins secreted by macrophages in the inflammatory process. Lymphokines 4: 377Google Scholar
  128. 128.
    Moscicki RA, Amento EP, Krane SM, Kurnick JT, Colvin RB (1983) Modulation of surface antigens of a human monocyte cell line, U937, during incubation with T lymphocyte-conditioned medium: detection of T4 antigen and its presence on normal blood monocytes. J Immunol 131: 743Google Scholar
  129. 129.
    Mowat AG, Baum J (1971) Chemotaxis of polymorphonuclear leucocytes from patients with rheumatoid arthritis. J Clin Invest 50: 2541Google Scholar
  130. 130.
    Mundy GR (1983) Monocyte-macrophage system and bone resorption. Lab Invest 49: 119Google Scholar
  131. 131.
    Nagase H, Jackson RC, Brinckerhoff CE, Vater CA, Harris ED Jr (1981) A precursor form of latent collagenase produced in a cell-free system with mRNA from rabbit synovial cells. J Biol Chem 256: 11951Google Scholar
  132. 132.
    Nagase H, Cawston TE, DeSilva M, Barrett AJ (1982) Identification of plasma kallikrein as an activator of latent collagenase in rheumatoid synovial fluid. Biochim Biophys Acta 702: 133Google Scholar
  133. 133.
    Nardella FA, Dayer JM, Roelke M, Krane SM, Mannik M (1983) Self-associating IgG rheumatoid factors stimulate monocytes to release prostaglandins and mononuclear cell factor that stimulates collagenase and prostaglandin production by synovial cells. Rheumatol Int 3: 183Google Scholar
  134. 134.
    Nedwin GE, Mohler MA, Luben RA (1983) Cloning of the coding sequences of human lymphokine, osteoclast-activating factor: a progress report. In: Oppenheim JJ, Cohen S, Landy M (eds) Interleukins, lymphokines and cytokines. Academic Press, New York, p 307Google Scholar
  135. 135.
    Nicola NA, Vadas M (1984) Hemopoietic colony-stimulating factors. Immunology Today 5: 76Google Scholar
  136. 136.
    Nimni ME (1983) Collagen: structure, function, and metabolism in normal and fibrotic tissues. Semin Arthritis Rheum 13: 1Google Scholar
  137. 137.
    Hiramatsu M, Kumegawa M, Hatakeyama K, Yajima T, Minami N, Kodama H (1982) Effect of epidermal growth factor on collagen synthesis in osteoblastic cells derived from newborn mouse calvaria. Endocrinology 6: 1810Google Scholar
  138. 138.
    Nosikov VV, Braga EA, Shivartston AL, Lvov VM, Gaitskhoki VS, Kiselev LL, Skobeleva NA, Frolova LG, Neifakh SA (1981) Structural organization of rat ceruloplasmin gene. Mol Biol 15: 651Google Scholar
  139. 139.
    Ohno S, Taniguchi T (1982) Inducer-responsive expression of the clone human interferon β1 gene introduced into cultured mouse cells. Nucleic Acids Res 10: 967Google Scholar
  140. 140.
    Opdenakker G, Weening H, Collen D, Billiau A, de Somer P (1982) Messenger RNA for human tissue plasminogen activator. Eur J Biochem 121: 269Google Scholar
  141. 141.
    Oppenheim JJ, Gery I (1982) Interleukin 1 is more than an interleukin. Immunology Today 3: 113Google Scholar
  142. 142.
    Parker CW (1982) The chemical nature of slow-reacting substances. In: Weissmann G (ed) Advances in inflammation research, vol 4. Raven Press, New York, p 1Google Scholar
  143. 143.
    Parrot DP, Goldberg RL, Kaplan SR, Fuller GC (1982) The effect of lymphokines on proliferation and collagen synthesis of cultured human synovial cells. Eur J Clin Invest 12: 407Google Scholar
  144. 144.
    Pennica D, Holmes WE, Kohr WJ, Harkins RN, Vehar GA, Ward CA, Bennett WF, Yelverton E, Seeburg PH, Heyneker HL, Goeddel DV, Collen D (1983) Cloning and expression of human tissue-type plasminogen detivator cDNA in E. coli. Nature 301: 214Google Scholar
  145. 145.
    Pinckard RN, McManus LM, Hanahan DJ (1982) Chemistry and biology of acetyl glyceryl ether phosphorylcholine (platelet-activating factor). In: Weissmann G (ed) Advances in inflammation research, vol 4. Raven Press, New York, p 147Google Scholar
  146. 146.
    Plant M, Lichenstein LM (1982) Histamine and immune responses. In: Ganellin CR, Parson ME (eds) Pharmacology of histamine receptors. Wright PSG, Bristol, p 392Google Scholar
  147. 147.
    Postlethwaite AE (1983) Cell-cell interaction in collagen biosynthesis and fibroblasts migration. In: Weissmann G (ed) Advances in inflammation research, vol 5. Raven Press, New York, p 27Google Scholar
  148. 148.
    Poubelle P, Beaulieu AD, Borgeat P (1984) Synthesis of leukotrienes (LTs) by synovial polymorphonuclear leukocytes (PMNL) and macrophages from patients with rheumatoid arthritis (RA). Arthritis Rheum 27: S 72Google Scholar
  149. 149.
    Poubelle P, Damon M, Blotman F, Dayer JM (1984) (to be published) Production of mononuclear cell factor (MCF) by mononuclear phagocytes from rheumatoid synovial fluid. J RheumatolGoogle Scholar
  150. 150.
    Poulter LW, Duke O, Hobbs S, Janossy G, Panayi G, Seymour G (1983) The involvement of interdigitating (antigen-presenting) cells in the pathogenesis of rheumatoid arthritis. Clin Exp Immunol 51: 247Google Scholar
  151. 151.
    Preble O, Balck R, Friedman R, Klippel JH, Vilcek J (1982) Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. Science 216: 429Google Scholar
  152. 152.
    Prickett JD, Robinson DR, Steinberg AD (1981) Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice. J Clin Invest 68: 556Google Scholar
  153. 153.
    Prickett JD, Robinson DR, Block KJ (1982) Enhanced production of IgE and IgG antibodies associated with a diet enriched in eicosapentaenoic acid. Immunology 46: 819Google Scholar
  154. 154.
    Pulkki K, Vuorio E, Jalava S (1983) The effect of rheumatoid synovial fluid macrophages on DNA, glycosaminoglycan and collagen synthesis by synovial fibroblasts. Rheumatol Int 3: 133Google Scholar
  155. 155.
    Raisz LG, Kream BE (1983) Regulation of bone formation. N Engl J Med 309: 29, 83Google Scholar
  156. 156.
    Raisz LG, Simmons HA, Sandberg AL, Canalis E (1980) Direct stimulation of bone resorption by epidermal growth factor. Endocrinology 107: 270Google Scholar
  157. 157.
    Ricca GA, Hamilton RW, McLeans JW, Conn A, Kalinyak JE, Taylor JM (1981) Rat α1-acid glycoprotein mRNA. J Biol Chem 256: 10362Google Scholar
  158. 158.
    Ritchie DG, Fuller GM (1983) Hepatocyte-stimulating factor: a monocyte-derived acute-phase regulatory protein. Ann NY Acad Sci 408: 490Google Scholar
  159. 159.
    Robert A, Grunberger G, Carpentier JL, Dayer JM, Orci L, Gorden P (1984) The insulin receptor of a human monocyte-like cell line: characterization and function. Endocrinology 114: 247Google Scholar
  160. 160.
    Robinson DR, Bastian D, Hamer PJ, Pichiarallo DM, Stephenson ML (1981) Mechanism of stimulation of prostaglandin synthesis by a factor from rheumatoid synovial tissue. Proc Natl Acad Sci USA 78: 5160Google Scholar
  161. 161.
    Robinson DR, Currau DP, Hamer PJ (1982) Prostaglandins and related compounds in inflammatory rheumatic diseases. In: Ziff M, Velo GP, Gorini S (eds) Advances in Inflammation Research, vol 3. Raven Press, New York, p 17Google Scholar
  162. 162.
    Rodriguez MA, Ceuppens JL, Goodwin JS (1982) Regulation of IgM rheumatoid factor production in lymphocyte cultures from young and old subjects. J Immunol 128: 2422Google Scholar
  163. 163.
    Rosenberg SA, Grimm EA, McGrogan M, Doyle M, Kawasaki E, Koths K, Mark DF (1984) Biological activity of recombinant human interleukin-2 produced in Escherichia coli. Science 223: 1412PubMedGoogle Scholar
  164. 164.
    Rothschild BM, Masi AT (1982) Pathogenesis of rheumatoid arthritis: a vascular hypothesis. Semin Arthritis Rheum 12: 11Google Scholar
  165. 165.
    Roubin R, Mencia-Huerta JM, Beneviste J (1982) Release of platelet-activating factor (PAE-acether) and leukotrienes C and D from inflammatory macrophages. Eur J Immunol 12: 141Google Scholar
  166. 166.
    Russell R, Raines E, Bowen-Pope D (1982) Growth factors from platelets, monocytes, and endothelium: their role in cell proliferation. Ann NY Acad Sci 397: 18Google Scholar
  167. 167.
    Saklatvala J, Curry VA, Sarsfield SJ (1983) Purification to homogeneity of pig leucocyte catabolin, a protein that causes cartilage resorption in vitro. Biochem J 215: 395Google Scholar
  168. 168.
    Saldeen T (1983) Vasoactive peptides derived from degradation of Fibrinogen and fibrin. Ann NY Acad Sci 408: 424Google Scholar
  169. 169.
    Samuelsson B (1983) Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220: 568Google Scholar
  170. 170.
    Schorlemmer HU, Pontz BF, Hanauske-Abel H, Seiler FR (1982) Activation of macrophages by cartilage specific collagen is triggered by endogenous C3: significance for rheumatoid arthritis. In: Ziff M, Velo GP, Gorini S (eds) Advances in inflammation research: rheumatoid arthritis, vol 3. Raven Press, New York, p 109Google Scholar
  171. 171.
    Scott DL, Walton KW (1984) The significance of fibronectin in rheumatoid arthritis. Semin Arthritis Rheum 13: 244Google Scholar
  172. 172.
    Scott J, Urdea M, Quiroga M, Sanchez-Pescador R, Fong N, Selby M, Rutter WJ, Bell GI (1983) Structure of a mouse submaxillary messenger RNA encoding epidermal growth factor and seven related proteins. Science 221: 236Google Scholar
  173. 173.
    Searles RP, Okudaira K, Savage SM, Goodwin JS (1983) Ia-specific antilymphocyte antibodies in rheumatoid arthritis. Arthritis Rheum 26: 486Google Scholar
  174. 174.
    Seitz M, Deimann W, Gram N, Hunstein W, Gemsa D (1982) Characterization of blood mononuclear cells of rheumatoid arthritis patients. I. Depressed lymphocyte proliferation and enhanced prostanoid release from monocytes. Clin Immunol Immunopathol 25: 405Google Scholar
  175. 175.
    Shiozawa S, Shiozawa K, Fujita T (1983) Presence of HLA-DR antigen on synovial type A and B cells: an immunoelectron microscopic study in rheumatoid arthritis, osteoarthritis and normal traumatic joints. Immunology 50: 587Google Scholar
  176. 176.
    Simmling-Annefeld M, Fassbenger HG (1979) Transformation of the capillary wall element in synovial tissue in rheumatoid arthritis. Z Rheumatol 38: 153Google Scholar
  177. 177.
    Snyder DS, Beller DI, Unanue ER (1982) Prostaglandins modulate macrophage Ia expression. Nature 299: 163Google Scholar
  178. 178.
    Staite ND, Ganczakowski M, Panayi GS, Unger A (1983) Prostaglandin-mediated immunoregulation: reduced sensitivity of in vitro immunoglobulin production to indomethacin in rheumatoid arthritis. Clin Exp Immunol 52: 535Google Scholar
  179. 179.
    Stastny P, Rosenthal M, Andreis M, Ziff M (1975) Lymphokines in the rheumatoid joint. Arthritis Rheum 18: 237Google Scholar
  180. 180.
    Stearman RS, Lowell CA, Pearson WR, Morrow JF (1982) Regulation of synthesis of amyloid A-related protein. Ann NY Acad Sci 389: 106Google Scholar
  181. 181.
    Steinmann BU, Abe S, Martin GR (1982) Modulation of type I and type III collagen production in normal and mutant human skin fibroblasts by cell density, prostaglandin E2 and epidermal growth factor. Collagen Rel Res 2: 185Google Scholar
  182. 182.
    Stuart JM, Postlethwaite AE, Townes AS, Kang AH (1980) Cell-mediated immunity to collagen α chains in rheumatoid arthritis and other rheumatic diseases. Am J Med 69: 13Google Scholar
  183. 183.
    Sztein MB, Steeg PS, Johnson HM, Oppenheim JJ (1984) Regulation of human peripheral blood monocyte DR antigen expression in vitro by lymphocytes and recombinant interferons. J Clin Invest 73: 556Google Scholar
  184. 184.
    Taniguchi T, Matsui H, Fujita T, Takaoka C, Kashima N, Yoshimoto R, Hamuro J (1983) Structure and expression of a cloned cDNA for human interleukin-2. Nature 302: 305Google Scholar
  185. 185.
    Teitelbaum SL, Kahn AJ (1980) Mononuclear phagocytes, osteoclasts and bone resorption. Mineral Electrolyte Metab 3: 2Google Scholar
  186. 186.
    Tence M, Polonsky J, Le Couedic JP, Benveniste J (1980) Release, purification, and characterization of platelet-activating factor (PAF). Biochemie 62: 251Google Scholar
  187. 187.
    Trang LE (1980) Prostaglandins and inflammation. Semin Arthritis Rheum 9: 153Google Scholar
  188. 188.
    Trechsel U, Dew G, Murphy G, Reynolds JJ (1982) Effects of products from macrophages, blood mononuclear cells and of retinol on collagenase secretion and collagen synthesis in chondrocyte culture. Biochim Biophys Acta 720: 364Google Scholar
  189. 189.
    Trentham DE, Dynesius RA, Rocklin RE, David JR (1978) Cellular sensitivity to collagen in rheumatoid arthritis. N Engl J Med 299: 327Google Scholar
  190. 190.
    Tucci A, Goldberger G, Whitehead AS, Kay RM, Woods DE, Colten HR (1983) Biosynthesis and postsynthetic processing of human C-reactive protein. J Immunol 131: 2416Google Scholar
  191. 191.
    Turner RA, Schumacher HR, Myers AR (1973) Phagocytic function of polymorphonuclear leukocytes in rheumatic diseases. J Clin Invest 52: 1632Google Scholar
  192. 192.
    Vadas P, Pruzanski W (1984) Role of extracellular phospholipase A2 in inflammation. In: Otterness I, Capetola R, Wong S (eds) Advances in inflammation research, vol 7. Raven Press, New York, p 51Google Scholar
  193. 193.
    Vadas P, Wasi S, Movat HZ, Hay JB (1981) Extracellular phospholipase A2 mediates inflammatory hyperemia. Nature 293: 583Google Scholar
  194. 194.
    Vane JR (1976) Prostaglandins as mediators of inflammation. In: Samuelsson B, Paoletti R (eds) Advances in prostaglandin and thromboxane research. Raven Press, New York, p 791Google Scholar
  195. 195.
    Vartio T, Vaheri A, von Essen R, Isomäki H, Stenman S (1981) Fibronectin in synovial fluid and tissue in rheumatoid arthritis. Eur J Clin Invest 11: 207Google Scholar
  196. 196.
    Vassalli JD, Dayer JM, Wohlwend A, Belin D (1984) Concomitant secretion of prourokinase and of a plasminogen activator-specific inhibitor by cultured human monocytes-macrophages. J Exp Med 159: 1653Google Scholar
  197. 197.
    Voelkel NF, Worthen S, Reeves JT, Henson PM, Murphy RC (1982) Non-immunological production of leukotrienes induced by platelet-activating factor. Science 218: 186Google Scholar
  198. 198.
    Wahl SM, Wahl LM (1981) Modulation of fibroblast growth and function by monokines and lymphokines. In: Pick E (ed) Lymphokines, vol 2. Academic Press, New York, p 179Google Scholar
  199. 199.
    Wahl SM, Wahl LM, McCarthy JB (1978) Lymphocyte-mediated activation of fibroblast proliferation and collagen production. J Immunol 121: 942Google Scholar
  200. 200.
    Weigle WO, Goodman MG, Morgan EL, Hugli TE (1983) Regulation of immune response by components of the complement cascade and their activated fragment. Springer Semin Immunopathol 6: 173Google Scholar
  201. 201.
    Weissmann G (1982) Activation of neutrophils and the lesions of rheumatoid arthritis. J Lab Clin Med 100: 322Google Scholar
  202. 202.
    Whitaker MO, Wyche A, Fitzpatrick F, Sprecher H, Needleman P (1979) Triene prostaglandins: prostaglandin D3 and icosapentanoic acid as potential antithrombotic substances. Proc Natl Acad Sci USA 76: 5919Google Scholar
  203. 203.
    Whitehead AS, Bruns GAP, Markham AF, Colten HR, Woods DE (1983) Isolation of human Creactive protein complementary DNA and localization of the gene to chromosome 1. Science 221: 69Google Scholar
  204. 204.
    Wilkins JA, Warrington RJ, Sigurdson SL, Rutherford WJ (1983) The demonstration of an interleukin-2-like activity in the synovial fluids of rheumatoid arthritis patients. J Rheumatol 10: 109Google Scholar
  205. 205.
    Windle JJ, Shin HS, Morrow JF (1984) Induction of interleukin 1 messenger RNA and translation in oocytes. J Immunol 132: 1317Google Scholar
  206. 206.
    Wood DD, Ihrie EJ, Dinarello CA, Cohen PL (1983) Isolation of an interleukin-1-like factor from human joint effusions. Arthritis Rheum 26: 975Google Scholar
  207. 207.
    Wooley PH, Pnay GS, Batchelor JR (1981) Lymphocytotoxins in RA: prevalence, lymphocyte specificity and HLA-DR antigens. Ann Rheum Dis 40: 154Google Scholar
  208. 208.
    Woolley DE (1984) Mammalian collagenases. In: Piez C, Reddi H, (eds) Extracellular matrix biochemistry. Elsevier, New York, p 119Google Scholar
  209. 209.
    Wysocki LJ, Sato VL (1978) “Panning” for lymphocytes: a method for cell selection. Proc Natl Acad Sci USA 75: 2844Google Scholar
  210. 210.
    Yang F, Brune JL, Baldwin WD, Barnett DR, Bowman BH (1983) Identification and characterization of human haptoglobin cDNA. Proc Natl Acad Sci USA 80: 5875Google Scholar
  211. 211.
    Yaron M, Yaron I, Smetana O, Eylan E, Herzberg M (1976) Hyaluronic acid produced by human synovial fibroblasts. Effect of polyinosinic-polycytidylic acid (poly I:C) and interferon. Arthritis Rheum 19: 1315Google Scholar
  212. 212.
    Yokota T, Lee F, Rennick D, Hill C, Arai N, Mosmann T, Nabel G, Cantor H, Arai KI (1984) Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth factor activity in monkey cells. Proc Natl Acad Sci USA 81: 1070Google Scholar
  213. 213.
    Yoneda T, Mundy GR (1982) Release of the lymphokine osteoclast activating factor requires cyclic AMP accumulation. Calcif Tissue Int 34: 204Google Scholar
  214. 214.
    Zavadil-Grob CM, Dayer JM (1981) Interactions between crystals mononuclear cell factor (MCF -IL1) and collagenase/PGE2 production by human dermal fibroblasts and synovial cells. Immunobiology 160: 132Google Scholar
  215. 215.
    Zeller J, Weissbarth E, Baruth B, Mielke H, Deicher H (1983) Serotonin content of platelets in inflammatory rheumatic diseases: correlation with clinical activity. Arthritis Rheum 26: 532Google Scholar
  216. 216.
    Zurier RB, Quagliata F (1971) Effect of prostaglandin E1 on adjuvant arthritis. Nature 234: 304Google Scholar
  217. 217.
    Zvaifler NJ (1973) Immunopathology of joint inflammation in rheumatoid arthritis. Adv Immunol 16: 265Google Scholar
  218. 218.
    Zvaifler NJ (1984) Immunopathology of inflammatory diseases: rheumatoid arthritis as an example. In: Otterness I, Capetola R, Wong S (eds) Advances in inflammation research, vol 7. Raven Press, New York, p 1Google Scholar

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • Jean-Michel Dayer
    • 1
  • Stephen Demczuk
    • 1
  1. 1.Division of Immunology and Allergy (Hans Wilsdorf Laboratory), Department of MedicineUniversity Hospital CantonalGeneva 4Switzerland

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