Lead arthropathy: a cause of delayed onset lead poisoning
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Abstract
Patients who suffer gun shot wounds often have retained bullet fragments within their bodies. These are usually of no clinical consequence. We describe three patients with retained bullets within their hip joints. One of these patients, who had extensive ground intra-articular bullet fragments and secondary osteoarthritis of the hip, presented with signs, symptoms, and laboratory data consistent with lead intoxication. The bullet and metallic fragments were removed surgically with good clinical response. Two patients whose bullets were implanted entirely within the femoral head and whose joints showed smaller degrees of lead fragmentation had no symptoms of lead intoxication. The degree of intra-articular fragmentation of the bullet and the surface area of lead exposed to synovial fluid are emphasized as decisive factors with respect to appropriate therapy.
Key words
Arthropathy, lead Intoxication, lead Trauma, gun shot woundPreview
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References
- 1.Ellis A. A case of probable lead poisoning, resulting fatally, from a bullet lodged in the knee joint twelve years previously. Boston Med Surg J 1874; 91:472–473.Google Scholar
- 2.Senturia HR. The roentgen findings in increased lead absorption due to retained projectiles. AJR 1942; 47:381–391.Google Scholar
- 3.Slavin RE, Swedo J, Cartwright J, Viegas S, Custer EM. Lead arthritis and lead poisoning following bullet wounds: a clinicopathologic, ultrastructural, and microanalytic study of two cases. Hum Pathol 1988; 19:223–235.Google Scholar
- 4.Switz DM, Elmorshidy ME, Deyerle WM. Bullets, joints and lead intoxication. Arch Intern Med 1976; 136:939–941.Google Scholar
- 5.Windler EC, Smith RB, Bryan WJ, Woods GW. Lead intoxication and traumatic arthritis of the hip secondary to retained bullet fragments. J Bone Joint Surg [Am] 1978; 60:254–255.Google Scholar
- 6.Dillman RO, Crumb CK, Lidsky MJ. Lead poisoning from a gunshot wound. Report of a case and review of the literature. Am J Med 1979; 66:509–514.Google Scholar
- 7.Grogan DP, Bucholz RW. Acute lead intoxication from a bullet in an intervertebral disc space. J Bone Joint Surg [Am] 1981; 63:180–1182.Google Scholar
- 8.Linden MA, Manton WI, Stewart M, Thal ER, Feit H. Lead poisoning from retained bullets. Pathogenesis, diagnosis, and management. Ann Surg 1982; 195:305–313.Google Scholar
- 9.Sclafani SJA, Vuletin JC, Twersky J. Lead arthropathy: arthritis caused by retained intra-articular bullets. Radiology 1985; 156:299–302.Google Scholar
- 10.Stromberg BV. Symptomatic lead toxicity secondary to retained shotgun pellets: case report. J Trauma 1990; 30:356–357.Google Scholar
- 11.Jensen SP, Richardson ML, Conrad EU, Lazerte GD. Case report 608: Retention of a bullet fragment within a traumatic pseudoarthrosis, resulting in lead arthropathy and lead intoxication. Skeletal Radiol 1990; 19:233–235.Google Scholar
- 12.DiMaio VJM, DiMaio SM, Garriot JC, Simpson P. A fatal case of lead poisoning due to a retained bullet. Am J Forensic Med Pathol 1983; 4:165–169.Google Scholar
- 13.McNally WD. Lead poisoning caused by a bullet embedded for twenty-seven years. Indus Med 1949; 18:77.Google Scholar
- 14.Primm DD. Lead arthorpathy — progressive destruction of a joint by a retained bullet. J Bone Joint Surg [Am] 1984; 66:292–294.Google Scholar
- 15.Roberts RD, Wong SW, Theil GB. An unusual case of lead arthropathy. Arthritis Rheum 1983; 26:1048–1051.Google Scholar
- 16.Aly MH, Kim HC, Renner SW, et al. Hemolytic anemia associated lead poisoning from shotgun pellets and the response to succimer treatment. Am J Hematol 1993; 44:280–283.Google Scholar
- 17.Beazley WC, Rosenthal RE. Lead intoxication 18 months after a gunshot wound. Clin Orthop Rel Res 1984; 190:199–203.Google Scholar
- 18.Leonard MH. The solution of lead by synovial fluid. Clin Orthop Rel Res 1969; 64:255–261.Google Scholar
- 19.Goldman A, Minkoff J, Price A, Krinick R. A posterior arthroscopic approach to bullet extraction from the hip. J Trauma 1987; 27:1294–1300.Google Scholar
- 20.Farber JM, Rafii M, Schwartz D. Lead arthropathy and elevated serum levels of lead after a gunshot wound of the shoulder. AJR 1994; 162:385–386.Google Scholar
- 21.Watson N, Sonogcharoen GP. Lead synovitis in the hand: a case report. J Hand Surg [Br] 1985; 10:423–424.Google Scholar
- 22.Viegas SF, Calhoun JH. Lead poisoning from a gunshot wound to the hand. J Hand Surg [Am] 1986; 11:729–732.Google Scholar
- 23.Selbst SM, Henretig F, Fee MA, Levy SE, Kitts AW. Lead poisoning in a child with a gunshot wound. Pediatrics 1986; 77:413–416.Google Scholar
- 24.McClure J. Intraarticular calcergy and its arthropathic sequelae. J Pathol 1984; 142:15–22.Google Scholar