The human aldose reductase gene maps to chromosome region 7q35
- Cite this article as:
- Graham, A., Heath, P., Morten, J.E.N. et al. Hum Genet (1991) 86: 509. doi:10.1007/BF00194644
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The human aldose reductase (AR) gene has been mapped to chromosome 7 using the polymerase chain reaction to specifically amplify the human AR sequence in hamster/human hybrid DNA and also in mouse/ human monochromosome hybrids. The assignment to chromosome 7 was confirmed by in situ hybridisation to human metaphase chromosomes using a novel, rapid hybridisation, method giving a regional localisation at 7q35.