Human Genetics

, Volume 85, Issue 5, pp 527–530

The human QARS locus: assignment of the human gene for glutaminyl-tRNA synthetase to chromosome 1q32–42

  • N. Kunze
  • E. Bittler
  • R. Fett
  • B. Schray
  • H. Hameister
  • K. H. Wiedorn
  • R. Knippers
Original Investigations

DOI: 10.1007/BF00194231

Cite this article as:
Kunze, N., Bittler, E., Fett, R. et al. Hum Genet (1990) 85: 527. doi:10.1007/BF00194231

Summary

We have used a cDNA encoding the core region of the human glutaminyl-tRNA synthetase to determine the chromosomal localization of the corresponding gene. Southern blots of restricted DNA from a panel of rodent-human cell lines and in situ chromosome hybridization gave identical results showing that the human gene locus for glutaminyl-tRNA synthetase resides on the distal long arm of chromosome 1. There are now nine mapped aminoacyl-tRNA synthetase genes in the human genome.

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • N. Kunze
    • 1
  • E. Bittler
    • 1
  • R. Fett
    • 1
  • B. Schray
    • 1
  • H. Hameister
    • 2
  • K. H. Wiedorn
    • 3
  • R. Knippers
    • 1
  1. 1.Fakultät für Biologie der UniversitätKonstanzFederal Republic of Germany
  2. 2.Abteilung Klinische Genetik der UniversitätUlmFederal Republic of Germany
  3. 3.Institut für Humangenetik und Genetische Poliklinik der UniversitätMarburgFederal Republic of Germany

Personalised recommendations