, Volume 40, Issue 2, pp 109–115 | Cite as

MHCDB — database of the human MHC

  • William R. Newell
  • John Trowsdale
  • Stephan Beck
Original Paper


Genetic and physical data relating to the human major histocompatibility complex (MHC) were compiled and analyzed, using a genome analysis program. The current contents of the database include: 1) location of over 100 genes and other markers; 2) location of over 250 YAC and cosmid clones; 3) 150 kilobases of genomic DNA sequence including full annotation (exon/intron boundaries, repeats, promoters, etc.); 4) cDNA sequences of currently-known class I and class II alleles; and 5) accompanying descriptive data — references, comments, laboratory addresses, and so on. The database allows rapid access, retrieval, and display of all these data, which should make it a useful tool for the study of the human MHC. MHCDB is publicly available and will be updated as new data become available.


Major Histocompatibility Complex cDNA Sequence Genome Analysis Analysis Program Descriptive Data 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • William R. Newell
    • 1
  • John Trowsdale
    • 1
  • Stephan Beck
    • 1
  1. 1.Imperial Cancer Research FundLondonUK

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