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Visual evoked potentials after photostress in newly diagnosed insulin-dependent diabetes patients

  • Vincenzo Parisi
  • Luigi Uccioli
  • Giovanna Monticone
  • Leoluca Parisi
  • Laura Durola
  • Claudio Pernini
  • Riccardo Neuschuler
  • Guido Menzinger
  • Massimo G. Bucci
Clinical Investigations

Abstract

•Background: The study was performed in order to ascertain whether electrophysiological abnormalities in visual function exist in newly diagnosed diabetic patients. •Methods: Visual evoked potentials (VEPs) were assessed under basal conditions and after photostress in normal control subjects and in newly diagnosed diabetic patients free of any fluorescein angiography signs of retinopathy. • Results: In basal conditions VEP P100 latency was significantly increased in the diabetic patients compared to controls (P<0.01), while N75-P100 amplitude was similar in both groups. After photostress N75-P100 amplitude (mean percentage decrement) was significantly higher in diabetic patients (P<0.01), while P100 latency (mean increment) and recovery time (time at which VEPs were superimposable on basal condition) were similar in the two groups. • Conclusions: The impaired basal VEPs suggest an early involvement of conduction in the optic nerve. In contrast, the preserved recovery time after photostress indicates that a short duration of disease does not induce physiopathological changes in macular function.

Keywords

Diabetic Patient Optic Nerve Recovery Time Fluorescein Angiography P100 Latency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • Vincenzo Parisi
    • 1
    • 2
  • Luigi Uccioli
    • 3
  • Giovanna Monticone
    • 3
  • Leoluca Parisi
    • 4
  • Laura Durola
    • 3
  • Claudio Pernini
    • 2
  • Riccardo Neuschuler
    • 2
  • Guido Menzinger
    • 3
  • Massimo G. Bucci
    • 1
  1. 1.Cattedra di Clinica Oculistica Universitá di Roma Tor VergataComplesso Integrato ColumbusRomeItaly
  2. 2.Divisione OculisticaOspedale FatebenefratelliRomeItaly
  3. 3.Cattedra di EndocrinologiaUniversitá di Roma Tor Vergata -Complesso Integrato ColumbusRomeItaly
  4. 4.II Clinica NeurologiaUniversity di Roma La SapienzaRomeItaly

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