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Psychopharmacology

, Volume 93, Issue 2, pp 223–225 | Cite as

Apomorphine-induced pecking in pigeons classically conditioned to environmental cues

  • U. Lindenblatt
  • J. D. Delius
Original Investigations

Abstract

The dopamine agonist apomorphine elicits protracted pecking when injected systemically (1 mg/kg) into pigeons. In two experiments it was investigated whether apomorphine would function as an unconditioned stimulus in the classical conditioning of pecking in these animals. An experimental design based on a differentiation procedure was used so that possible pseudoconditioning effects were controlled. Two differently coloured test chambers served as negative (CS-) and positive conditioned (CS+) stimuli. During the training phase the subjects experienced the former while injected with saline, and the latter while injected with apomorphine. In later tests not involving any injections the pigeons made significantly more pecks (conditioned response) in the CS+ chamber than in the CS-chamber. In the first and second experiments the conditioned stimuli were, respectively, discrete and diffuse visual cues, but both had similar effects. The conditioning obtained may explain sensitization effects that are observed with repeated apomorphine injections. Apomorphine probably also functions as a positive reinforcer for instrumental conditioning in pigeons.

Key words

Dopamine agonist Apomorphine Pavlovian conditioning Pecking Pigeons 

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References

  1. Amsler C (1923) Beiträge zur pharmakologie des Gehirns. Arch Exp Pathol Pharmakol 97:1–27Google Scholar
  2. Basten-Kreft A (1977) Apomorphin-induziertes Verhalten bei Tauben. Diplomarbeit, Ruhr-Universität, BochumGoogle Scholar
  3. Baxter BL, Gluckman MI, Stein L, Scerni RA (1974) Self-injection of apomorphine in the rat: positive reinforcement by a dopamine receptor stimulant. Pharmacol Biochem Behav 2:387–392Google Scholar
  4. Brunelli M, Magni F, Moruzzi G, Musumeci D (1975) Apomorphine pecking in the pigeon. Arch Ital Biol 113:303–325Google Scholar
  5. Carey RJ (1986) Conditioned rotational behavior in rats with unilateral 6-hydroxydopamine lesions of the substantia nigra. Brain Res 365:379–382Google Scholar
  6. Costentin J, Protais P, Schwartz JC (1975) Rapid and dissociated changes in sensitivities of different receptors in mouse brain. Nature 257:405–407Google Scholar
  7. Davey G (1981) Animal learning and conditioning. Macmillan, LondonGoogle Scholar
  8. Delius JD (1985) The peck of the pigeon: free for all. In: Lowe CF, Richelle M, Blackman DE, Bradshaw CM (eds) Behaviour analysis and contemporary psychology. Erlbaum, New York, pp 53–81Google Scholar
  9. Deviche P (1984) Administration of small doses of apomorphine attenuates feeding in non-deprived pigeons. Physiol Behav 33:581–585Google Scholar
  10. Ellinwood EH (1971) “Accidental conditioning” with chronic methamphetamine intoxication: implications for a theory of drug habituation. Psychopharmacology 21:131–138Google Scholar
  11. Garcia J, Ervin FR, Koelling RA (1966) Learning with long delay of reinforcement. Psychon Sci 5:121–123Google Scholar
  12. Lindenblatt U (1986) Die dopaminerge Auslösung des Pickverhaltens bei Tauben. Dissertation, Ruhr-Universität, BochumGoogle Scholar
  13. Machlis L (1980) Apomorphine: effects on the timing and sequencing of pecking behavior in chicks. Pharmacol Biochem Behav 13:331–336Google Scholar
  14. Pavlov IP (1927) Conditioned reflexes (G.V. Anrep. transl.) Oxford University Press, LondonGoogle Scholar
  15. Siegel S (1982) Pharmacological habituation and learning. In: Commons ML, Herrnstein RI, Wagner AR (eds) Quantitative analyses of behavior III: Acquisition. Ballinger, Cambridge, Massachusetts, pp 195–217Google Scholar
  16. Tilson HA, Rech H (1973) Conditioned drug effects and absence of tolerance to d-apomorphine induced motor activity. Pharmacol Biochem Behav 1:149–153Google Scholar

Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • U. Lindenblatt
    • 1
  • J. D. Delius
    • 1
  1. 1.Experimentelle Tierpsychologie, Psychologisches InstitutRuhr-UniversitätBochumFederal Republic of Germany

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