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Immunogenetics

, Volume 42, Issue 5, pp 444–445 | Cite as

A polymorphic dinucleotide repeat in the human IL-10 promoter

  • Joyce Eskdale
  • Grant Gallagher
Sequence Register

Keywords

Dinucleotide Dinucleotide Repeat Polymorphic Dinucleotide Polymorphic Dinucleotide Repeat 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Cush, J. C., Splawski, J. B., Thomas, R., McFarlin, J. E., Schulze-Koops, H., Davis, L. S., Fujita, K., and Lipsky, P. E. Elevated levels of interleukin-10 in patients with rheumatoid athritis. Arth Rheum 38: 96–104, 1995Google Scholar
  2. Fiorentino, D. F., Zlotnic, A., Viera, P., Mosmann, T. R., Howard, M., Moore, K. W., and O'Garra, A. IL-10 acts on the antigen presenting cell to inhibit cytokine production by Th1 cells. J Immunol 146: 3444–3451, 1991Google Scholar
  3. Kube, D., Platzer, C., von, Knethen, A., Straub, H., Bohlen, H., Hafner, M., and Tesch, H. Isolation of the human interleukin 10 promoter. Characterisation of the promoter activity in Burkitts's lymphoma cell lines. Cytokine 7: 1–7, 1995CrossRefPubMedGoogle Scholar
  4. Luscher, U., Filgueira, L., Juretic, A., Zuber, M., Luscher, N. J., Heberer, M., and Spagnoli, G. C. The pattern of cytotokine gene expression in freshly excised human metastatic melonoma suggests a state of reversible anergy of tumour infiltrating lymphocyres. Int J Cancer 57: 612–619, 1994Google Scholar
  5. Marsh, D. G., Neely, J. D., Breazeale, D. R., Ghosh, B., Freidhoff, L. R., Ehrlich-Kautzky, E., Schou, C., Krishnaswamy, G., and Beaty, T. Linkage analysis of IL_4 and other chromosome 5q31.1 markers and total serum immunoglobulin concentrations. Science 264: 1152–1156, 1994Google Scholar
  6. Moore, K. W., O'Garra, A., de Waal-Malefyt, R., Viera, P., and Mosmann, T. R. IL-10. Annu Rev Immunol 11: 165–290, 1993Google Scholar
  7. Pociot, F., Briant, L., Jongeneel, C. V., Molvig, J., Worsaae, H., Abbal, M., Thomsen, M., Nerup, J., and Cambon-Thomsen, A. Association of tumour necrosis factor (TNF) and class II major histocompatibility complexc alleles with the secretion of TNF-α and TNF-β by human mononucleat cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 23: 224–231, 1993PubMedGoogle Scholar
  8. Udalova, I. A., Nedospasov, S. A., Webb, G. C., Chaplin, D. D., and Terutskaya, R. L. Highly informative typing of the human TNF locus using six adjacent polymorphic markers. Genomics 16: 180–186, 1993Google Scholar
  9. Wanidworanum, C. and Strober, W. Predominant role of tumour necrosis factor-α in human monocyte IL-10 synthesis. J Immunol 151: 6853–6861, 1993Google Scholar

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • Joyce Eskdale
    • 1
  • Grant Gallagher
    • 1
  1. 1.Queen Elizabeth Building, Glasgow Royal InfirmaryUniversity of Glasgow Department of SurgeryGlasgowScotland

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