, Volume 42, Issue 5, pp 442–443 | Cite as

Variable domain sequences of mAb with high affinity for a linear oligopeptide

  • Thom'aš Hanke
  • Richard E. Randall
Sequence Register


Variable Domain Oligopeptide Domain Sequence Variable Domain Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Hanke, T., Botting, C., Green, E. A., Szawlowski, P. W., Rud, E., and Randall, R. E. Expression and purification of nonglycosylated SIV proteins, and their use in induction and detection of SIV-specific immune responses. AIDS Res Hum Restroviruses 10: 664–674, 1994Google Scholar
  2. Hanke, T., Szawlowski, P., and Randall, R. E. Construction of solid matirx-antibody-antigen complexes containing simian immunodeficiency virus p27 using tag-specific monolconal antibody and tag-linked antigen. J Gen Virol 73: 653–660, 1992Google Scholar
  3. Hanke, T., Young, D. F., Doyle, C., Jones, I., and Randall, R. E. Attaachment of an oligopeptide epitope to the C-terminus of recombinant SIV pg160 facilities the construction of SMAA complexes while preserving CD4 binding. J Virol Methods 53: 149–156, 1995Google Scholar
  4. Jones, S. T. and Bendig, M. Rapid PCR cloning of full-length mouse immunoglobulin variable regions. Bio/Technology 9: 88–89, 1991Google Scholar
  5. Hoogenboom, H. R., Griffiths, A. D., Johnson, K. S., Chiswell, D. J., Hudson, P., and Winter, G. Multi-sibunit protein on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucleic Acids Res 19: 4133–4137, 1991Google Scholar
  6. Randall. R. E. and Young, D. F. Solid matrix-antibody-antigen complexes induce antigen-specific CD8+ cells that clear a presistent paramyxovirus infection. J Virol 65: 719–726, 1991Google Scholar
  7. Randall, R. E., Young, D. F. Goswami, K. K., and Russell, W. C. Isolation and characterization of monoclonal antibodies to simian virus 5 and their use in revealing antigenic differences between human, canine and simian isolates. J Gen Virol 68: 2769–2780, 1987Google Scholar
  8. Souther, J. A., Young, D. F., Heaney, F., Baumgartner, W. K., and Randall, R. E. Identification of an epitope on the P and V proteins of simian virus 5 that distinguishes between two isolates with different biological characteristics. J Gen Virol 72: 1551–1557, 1991Google Scholar
  9. Winter, G. and Milstein, C. Man-made antibodies. Nature 349: 293–299, 1991Google Scholar

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • Thom'aš Hanke
    • 1
  • Richard E. Randall
    • 1
  1. 1.Division of Cell and Molecular BiologyUniversity of St. AndrewsSt. AndrewsUK

Personalised recommendations