Pediatric Surgery International

, Volume 11, Issue 4, pp 269–271

Regional lymphadenitis following BCG vaccination

  • C. Merry
  • R. J. Fitzgerald
Original Article


A cluster of cases of lymphadenitis occurred in Dublin following vaccination with a newly introduced Copenhagen 1331 strain of Bacille Calmette-Guerin (BCG) vaccine during 1989. All cases of BCG lymphadenitis presenting to paediatric surgical clinics over an 11-year period were reviewed to determine the optimum treatment for this problem. Seventeen patients are included, 16 of whom received vaccine in the newborn period; 1 received BCG at 8 months. Nine were treated by initial operation, 6 with antituberculous drugs, and 2 were observed without specific therapy. All but 1 of the medically treated patients and both patients who received observation only required operation for failure to resolve or progression of disease. The best results were obtained with excision and primary closure. We conclude that although sponteneous resolution occurs in a majority of all cases of BCG lymphadenitis in infants, in those patients with more severe disease who require surgical referral, a short trial of anti-microbial therapy is indicated. Patients who fail to improve or develop complications are then best treated by surgical excision of the involved nodes.

Key words

Bacille Calmette-Guerin BCG vaccine Infant Lymph nodes 


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  1. 1.
    Banani SA, Alborzi A (1994) Needle aspiration for suppurative post-BCG adenitis. Arch Dis Child 71: 446–447PubMedCrossRefGoogle Scholar
  2. 2.
    Caglayan S, Yegin O, Kayran K, Timocin N, Kasirga E, Gun M (1987) Is medical therapy effective for regional adenitis following BCG vaccination? Am J Dis Child 141: 1213–1214PubMedGoogle Scholar
  3. 3.
    Hanley SP, Gumb J, Mac Farlane JT (1985) Comparison of erythromycin and isoniazid in treatment of adverse reactions to BCG vaccination. BMJ 290: 970PubMedCrossRefGoogle Scholar
  4. 4.
    Hengster P, Schnapka J, Fille M, Menardi G (1992) Occurrence of suppurative lymphadenitis after a change in BCG vaccination. Arch Dis Child 67: 952–955PubMedCrossRefGoogle Scholar
  5. 5.
    Ildirim I, Sapan N, Cavusoglu B (1992) Comparison of BCG vaccination at birth and at third month of life. Arch Dis Child 67: 80–82PubMedCrossRefGoogle Scholar
  6. 6.
    Lotte A, Wazs-Hockert O, Poisson N, Engbaek H, Landmann H, Quast U, et al (1988) Second IUALTD study on complications induced by intradermal BCG vaccination. Bull Int Union Tubercul Lung Dis 63: 47–59Google Scholar

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • C. Merry
    • 1
  • R. J. Fitzgerald
    • 1
    • 2
  1. 1.Children's Research CentreOur Lady's Hospital for Sick ChildrenDublin 12Ireland
  2. 2.The Children's HospitalDublin 1Ireland

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