Journal of Neuro-Oncology

, Volume 30, Issue 3, pp 237–242 | Cite as

Anaplastic (malignant) ganglioglioma arising from heterotopic grey matter nodules

  • Philippe Demaerell
  • Myriam Droessaert
  • Martin Lammens
  • Johan Menten
  • Bart Nuttin
  • Rudy Verbeecks
  • Guy Wilms
  • Albert L. Baert
Clinical Study

Summary

Anaplastic ganglioglioma is a rare malignant neoplasm. The short clinical course and the anaplastic histological features are characteristics of malignant ganglioglioma. Immunohistochemistry is necessary for the final diagnosis. The MRI appearances are described here for the first time in literature. Nodular grey matter heterotopias had been demonstrated and the patient developed an anaplastic ganglioglioma two years later, on the same place where the grey matter heteropias had been seen. This finding supports the hypothesis that these tumours may arise from grey matter nodules.

Key words

brain neoplasms MR — brain abnormalities 

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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Philippe Demaerell
    • 1
  • Myriam Droessaert
    • 1
  • Martin Lammens
    • 2
    • 6
  • Johan Menten
    • 3
  • Bart Nuttin
    • 4
  • Rudy Verbeecks
    • 5
  • Guy Wilms
    • 1
  • Albert L. Baert
    • 1
  1. 1.Department of RadiologyLeuvenBelgium
  2. 2.Department of NeuropathologyLeuvenBelgium
  3. 3.Department of OncologyLeuvenBelgium
  4. 4.Department of NeurosurgeryLeuvenBelgium
  5. 5.Laboratory for Medical Imaging ResearchLeuvenBelgium
  6. 6.University Hospitals K.U.L.LeuvenBelgium
  7. 7.PAMMEindhovenThe Netherlands
  8. 8.Department of RadiologyUniversity HospitalsLeuvenBelgium

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