Journal of Molecular Evolution

, Volume 38, Issue 6, pp 602–609 | Cite as

Relationship among coelacanths, lungfishes, and tetrapods: A phylogenetic analysis based on mitochondrial cytochrome oxidase I gene sequences

  • Shin-ichi Yokobori
  • Masami Hasegawa
  • Takuya Ueda
  • Norihiro Okada
  • Kazuya Nishikawa
  • Kimitsuna Watanabe


To clarify the relationship among coelacanths, lungfishes, and tetrapods, the amino acid sequences deduced from the nucleotide sequences of mitochondrial cytochrome oxidase subunit I (COI) genes were compared. The phylogenetic tree of these animals, including the coelacanth Latimeria chalumnae and the lungfish Lepidosiren paradoxa, was inferred by several methods. These analyses consistently indicate a coelacanth/lungfish clade, to which little attention has been paid by previous authors with the exception of some morphologists. Overall evidence of other mitochondrial genes reported previously and the results of this study equally support the coelacanth/lungfish and lungfish/tetrapod clades, ruling out the coelacanth/tetrapod clade.

Key words

Origin of tetrapods Coelacanth Latimeria chalumnae Lungfish Lepidosiren paradoxa Cytochrome oxidase subunit I (COI) Maximum likelihood inference of protein phylogeny 


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Copyright information

© Springer-Verlag New York Inc 1994

Authors and Affiliations

  • Shin-ichi Yokobori
    • 1
    • 3
  • Masami Hasegawa
    • 2
  • Takuya Ueda
    • 3
  • Norihiro Okada
    • 1
  • Kazuya Nishikawa
    • 1
  • Kimitsuna Watanabe
    • 3
  1. 1.Department of Biological Sciences, Faculty of Bioscience and BiotechnologyTokyo Institute of TechnologyYokohamaJapan
  2. 2.The Institute of Statistical MathematicsMinato-ku, TokyoJapan
  3. 3.Department of Industrial Chemistry, Faculty of EngineeringUniversity of TokyoTokyoJapan

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