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Applied Microbiology and Biotechnology

, Volume 36, Issue 4, pp 515–517 | Cite as

Controlled biosynthesis of Val7- and Leu7-surfactins

  • Françoise Peypoux
  • Georges Michel
Applied Microbial and Cell Physiology

Summary

Surfactin was found to consist of a mixture of two groups of homologous lipopeptides differing by their peptide sequence; Val7-surfactin was recently characterized as a minor companion of the previously described Leu7-surfactin. The addition of various α-amino acids to the culture media led to variations in the production ratios of the two congeners. The supplementation of l-valine or l-isoleucine to the culture medium resulted in a selective enhancement of the production of the Val7-surfactin whereas this production was very low when l-leucine was the nitrogen source in the culture medium.

Keywords

Nitrogen Peptide Val7 Nitrogen Source Peptide Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag 1992

Authors and Affiliations

  • Françoise Peypoux
    • 1
  • Georges Michel
    • 1
  1. 1.Laboratoire de Biochimie MicrobienneUniversité Claude Bernard Lyon IVilleurbanne CedexFrance

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