Applied Microbiology and Biotechnology

, Volume 34, Issue 5, pp 613–616 | Cite as

Response of mammalian cells to shear stress

  • G. Kretzmer
  • K. Schügerl
Biochemical Engineering


The influence of shear forces on adherent mammalian cells was investigated by means of a developed flow chamber. The viability of the cells decreased with increasing exposure level and duration. Additional, changes in the morphology of the cells due to the shear forces were observed.


Shear Stress Mammalian Cell Shear Force Exposure Level Flow Chamber 
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Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • G. Kretzmer
    • 1
  • K. Schügerl
    • 1
  1. 1.Institut für Technische ChemieUniversität HannoverHannover 1Federal Republic of Germany

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