Journal of Molecular Evolution

, Volume 35, Issue 6, pp 492–501 | Cite as

Evidence for retrotranscription of protein-coding genes in the Drosophila subobscura genome

  • Gemma Marfany
  • Roser Gonzàlez-Duarte


Evidence is provided for the presence of retrosequences (also named retroposons) arising from Adh in the Drosophila subobscura genome. Restriction analysis and primary structure of two different retrosequence-containing clones, S812 and S135, are reported. The fact that these retrosequences lack introns and a recognizable promoter strongly supports their retrotranscriptional origin. Adjacent to the two retrosequences analyzed, a middle repetitive DNA element has been found which bears no clear similarity to any sequence reported to date in the GenBank/EMBL Data Library. A comparative analysis of these retrosequences with the functional Adh gene of D. subobscura is presented. In addition, a model concerning the origin, functionality, and propagation of these genome elements is discussed.

Key words

Drosophila subobscura Adh Retrosequence Retropseudogene Repetitive DNA Evolutionary patterns 


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Copyright information

© Springer-Verlag New York Inc 1992

Authors and Affiliations

  • Gemma Marfany
    • 1
  • Roser Gonzàlez-Duarte
    • 1
  1. 1.Departament de Genètica, Facultat de BiologiaUniversitat de BarcelonaBarcelonaSpain

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