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Documenta Ophthalmologica

, Volume 59, Issue 4, pp 309–321 | Cite as

Bilateral oculomotor abnormalities in strabismic amblyopes: evidence for a common central mechanism

  • Harold E. Bedell
  • Merton C. Flom
Article

Abstract

The preferred eyes of strabismic amblyopes, generally presumed to be normal, have been implicated by recent studies as manifesting oculomotor abnormalities. We sought to determine whether these motor abnormalities occurred together and, if so, whether they could be related to a single underlying deficit. Occurring together in the preferred eyes of our strabismic amblyopes were: unsteady fixation (consisting of nasal drifts alternating with temporal saccades), minute fixational eccentricity (as indicated by eccentric directionalization of the Maxwell spot) and asymmetries of pursuit tracking. These motor abnormalities of the preferred eye are attributable to the presence of high-velocity nasal drifts. Since nasal drifts also account for several qualitatively similar motor abnormalities exhibited under monocular conditions by the fellow amblyopic eye, we conclude that a centrally-generated nasal drift bias is responsible for anomalous oculomotor behaviors of both eyes of strabismic amblyopes.

Keywords

Public Health Central Mechanism Motor Abnormality Similar Motor Oculomotor Behavior 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Bedell HE and Flom MC (1981) Monocular spatial distortion in strabismic amblyopia. Invest Ophthal Vis Sci 20:263–268Google Scholar
  2. Bedell HE and Flom MC (1983) Normal and abnormal space perception. Amer J Optom Physiol Opt 60:426–435Google Scholar
  3. Burian HM and Cortimiglia RM (1962) Visual acuity and fixation pattern in patients with strabismic amblyopia. Amer Orthopt J 12:169–174Google Scholar
  4. Ciuffreda K (1977) Eye movements in amblyopia and strabismus. Doctoral dissertation, School of Optometry, University of California, BerkeleyGoogle Scholar
  5. Ciuffreda KJ, Kenyon RV and Stark L (1979) Fixational eye movements in amblyopia and strabismus. J Amer Optom Ass 50: 1251–1258Google Scholar
  6. Ditchburn RW and Foley-Fisher JA (1967) Assembled data in eye movements. Optica Acta14:113–118Google Scholar
  7. Flom MC and Weymouth FW (1961) Centricity of Maxwell's spot in strabismus and amblyopia. Arch Ophthal 66:136–144Google Scholar
  8. Fukai S, Tsutsui J and Nakamura Y (1976) Abnormal pursuit movements of the fellow eye in amblyopia with strabismus. In: Orthoptics, Past, Present, Future, eds: S Moore, J Mein and L Stockbridge. Miami, Florida, Symposia Specialists, pp 75–91Google Scholar
  9. Hermann JS and Priestley BS (1965) Bifoveal instability. The relationship to strabismic amblyopia. Amer J Ophthal 60:452–459Google Scholar
  10. Kandel GL, Grattan PE and Bedell HE (1977) Monocular fixation and acuity in amblyopic and normal eyes. Amer J Optom Physiol Opt 54:598–608Google Scholar
  11. Lawwill T (1966) The fixation pattern of the light-adapted and dark-adapted amblyopic eye. Amer J Ophthal 61:1416–1419Google Scholar
  12. Miles WR (1949) On the central zone of the human fovea. Science 109:441–442Google Scholar
  13. von Noorden GK and Burian HM (1962) An electro-opthalmographic study of the behavior of the fixation of amblyopic eyes in light- and dark-adapted state: A preliminary report. Amer J Ophthal 46:68–77Google Scholar
  14. von Noorden G and Mackensen G (1962) Pursuit movements of normal and amblyopic eyes. An electro-ophthalmographic study. II. Pursuit movements in amblyopic patients. Amer J Ophthal 52:477–487Google Scholar
  15. von Noorden GK (1970) Etiology and pathogenesis of fixation anomalies in strabismus: IV. Roles of suppression scotoma and of motor factors. Amer J Ophthal 69:236–245Google Scholar
  16. Puckett J and Steinman RM (1969) Tracking eye movements with and without saccadic correction. Vision Res 9:695–703Google Scholar
  17. Schor CM and Flom MC (1974) Eye position control and visual acuity in strabismus and amblyopia. In: Basic Mechanisms of Ocular Motility and Their Clinical Implications, eds: G Lennerstrand and P Bach-y-Rita. New York, Pergamon Press, pp 555–559Google Scholar
  18. Schor CM (1975) A directional impairment of eye movement control in strabismus amblyopia. Invest Ophthal 14:692–697Google Scholar
  19. Schor CM and Hallmark W (1978) Slow control of eye position in strabismic amblyopia. Invest Ophthal Vis Sci 17:577–581Google Scholar
  20. Schor CM and Levi DM (1980) Disturbances of small field horizontal and vertical optokinetic nystagmus in amblyopia. Invest Ophthal Vis Sci 19:668–683Google Scholar
  21. Schor CM (1983) Subcortical binocular suppression affects the development of latent and optokinetic nystagmus. Amer J Optom Physiol Opt 60:481–502Google Scholar
  22. Stark L (1971) The control system for versional eye movements. In: The Control of Eye Movements, eds: P Bach-y-Rita and C Collins. New York, Academic Press, pp 363–428Google Scholar
  23. Steinman RM, Cunitz RJ, Timberlake GT and Herman M (1967) Voluntary control of microsaccades during maintained monocular fixation. Science 155:1577–1579Google Scholar
  24. Westheimer G and McKee SP (1975) Visual acuity in the presence of retinal image motion. J Opt Soc Amer 65:847–850Google Scholar
  25. Windsor CE, Burian HM and Milojevic B (1968) Modification of latent nystagmus. Arch Ophthal 80:657–663Google Scholar
  26. Yee RD, Wong EK, Baloh RW and Honrubia V (1976) A study of congenital nystagmus: waveforms. Neurology 26:326–333Google Scholar

Copyright information

© Dr W. Junk Publishers 1985

Authors and Affiliations

  • Harold E. Bedell
    • 1
  • Merton C. Flom
    • 1
  1. 1.From College of OptometryUniversity of HoustonUniversity Park, HoustonUSA

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