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Documenta Ophthalmologica

, Volume 79, Issue 2, pp 125–139 | Cite as

Relationships between the electroretinogram a-wave, b-wave and oscillatory potentials and their application to clinical diagnosis

  • Husam Asi
  • Ido Perlman
Article

Abstract

The electroretinogram is the electrical response of the retina to a light stimulus. The amplitude and temporal pattern of its components, the a-wave, the b-wave and the oscillatory potentials, depend on the functional integrity of the retina, on the intensity of test flash reaching the retina and on the ambient illumination. The latter contributions to the normal variability in the electroretinogram can be circumvented by constructing the relationships between the different electroretinogram waves. The electroretinogram responses were recorded from 18 dark-adapted subjects with normal vision. The slope of the a-wave and the amplitude of the b-waves were measured in the time domain. The oscillatory potentials were isolated by a digital filter and were transformed to the frequency domain for quantitative measurement. The relationship between each pair of variables could be fitted by linear segments. Our findings suggest that this mode of electroretinogram analysis can be useful in localizing the site of action of retinal disorders and that the relationship between the a-wave slope and the power density of the oscillatory potentials is a useful index for identifying disorders of the inner retina.

Key words

a-wave b-wave electroretinogram oscillatory potentials retina 

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Copyright information

© Kluwer Academic Publishers 1992

Authors and Affiliations

  • Husam Asi
    • 1
  • Ido Perlman
    • 1
  1. 1.Department of Physiology and BiophysicsThe Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences, Technion-Israel Institute of TechnologyHaifaIsrael

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