Crystallization mechanisms of calcium phosphate cement for biological uses

  • J. L. Lacout
  • E. Mejdoubi
  • M. Hamad
Article

Abstract

Self-setting calcium phosphate cement for dental or surgical applications can be prepared by the addition of a liquid to a mixture of acidic and basic calcium phosphate. After hardening, the final compound becomes hydroxyapatite. Using an orthogonal central composite plan, the main factors which control the setting and the final hardness of the cement were defined and models are proposed. The mechanisms of crystallization, the role of free and linked water, and the nature of the final and intermediate compounds are described.

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References

  1. 1.
    W. E. BROWN and L. C. CHOW, J. Dent. Res. 62 (1983) 672.Google Scholar
  2. 2.
    A. A. MIRTCHI, J. LEMAITRE and E. MUNTING, Biomaterials 11 (1990) 83–88.Google Scholar
  3. 3.
    J. L. LACOUT, E. MEJDOUBI, Procédé d'obtention d'hydroxyapatite phosphocalcique, application au comblement esseux ou au moulage de piéces et produits utilisés-Brevet Fr 92.09019/PCT/FR.Google Scholar
  4. 4.
    J. GOUPY. La méthode des plans d'expériences. Dunod, (1988).Google Scholar
  5. 5.
    G. SADO, M. C. SADO. Les plans d'expériences. De l'expérimentation à l'assurance qualité AFNOR technique (1991).Google Scholar
  6. 6.
    R. A. YOUNG and W. E. BROWN Structures of biological minerals, biological mineralization and demineralization. edited by G. H. NANCOLLAS (Dahlem Konferenzen, Springer Verlag, Heidelberg, 1982) pp. 101–141.Google Scholar

Copyright information

© Chapman & Hall 1996

Authors and Affiliations

  • J. L. Lacout
    • 1
  • E. Mejdoubi
    • 2
  • M. Hamad
    • 2
  1. 1.Laboratoire des Matériaux-Physico-Chimie des SolidesENSCT-INP Toulouse-URA CNRS 445ToulouseFrance
  2. 2.Laboratoire de Chimie Physique GénéraleUniversité Mohammed VRabat Agdal-Maroc(Morocco)

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