European Journal of Epidemiology

, Volume 6, Issue 4, pp 382–385

Neosartorya fischeri var fischeri (Wehmer) Malloch and Cain 1972 (Anamorph: Aspergillus fischerianus Samson and Gams 1985) as a cause of mycotic keratitis

  • G. Coriglione
  • G. Stella
  • L. Gafa
  • G. Spata
  • S. Oliveri
  • A. A. Padhye
  • L. Ajello
Article

Abstract

The first case of mycotic keratitis caused by Neosartorya fischeri var. fischeri the telemorph of Aspergillus fischerianus, is described. The patient, a 62-year-old man, had no history of trauma to his infected left eye. The infection progressed despite treatment with ketoconazle and the eye had to be eviscerated.

Histological studies revealed the presence of hyaline, septate mycelium in the eye tissue. Cultures gave rise to a thermotolerant mould that developed both its asexual and sexual forms. The isolate was identified on the basis of the morphologic features of its anamorphic and teleomorphic states.

In the literature only seven other species of Aspergillus have been unequivocally reported as causing mycotic keratitis.

Key words

Mycotic keratitis Neosartorya fischeri (Aspergillus fischerianus) 

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References

  1. 1.
    Affeldt J.C., Flyne H.W., Forster R.K., Mandellbaum S., Clarkson J.G. and Jarus G.D. (1987): Microbiol endophthalmitis resulting from ocular trauma. -Opthalmology 94: 407–413.Google Scholar
  2. 2.
    Arora R., Venkateswarlu R. and Mahajan V.M. (1988): Keratomycosis — a retrospective histopathologic and microbiologic analysis. - Annals Ophthal. 20: 306–310, 315.Google Scholar
  3. 3.
    Domsch K.H., Gams W. and Anderson T.H. (1980): Compendium of Soil Fungi. Vol. 1: 76. - Academic Press, New York.Google Scholar
  4. 4.
    Gerber J., Chomicki J., Brandsberg J.W., Jones R. and Hammerman K.J. (1973): Pulmonary aspergillosis caused by Aspergillus frscheri var. spinosus. - Amer. J. Clin. Path. 60: 861–886.Google Scholar
  5. 5.
    Hanish S.J., Perlmutter J.C., Boucher C. et al. (1984): Exogenous Aspergillus endophthalmitis. - Ann. Ophthal. 16: 417–419.Google Scholar
  6. 6.
    Leber T. (1979):Keratomycosis asperigillina als Ursache von Hypoyonkeratitis. - Alberecht von Graefe's Arch. fur Ophthalmologie 25: 285–301.Google Scholar
  7. 7.
    Malloch D. and Cain R.F. (1972): The Trichocomataceae: Ascomycetes with Aspergillus, Paecilomyces, and Penicillium imperfect states. - Can. J. Bot. 50: 2613–2628.Google Scholar
  8. 8.
    Nolard N., Detandt M. and Beguin H. (1988): Ecology of Aspergillus species in the human environment. In: Aspergillus and Aspergillosis. (H.V. Bossche, D.W.R. Mackenzie and G. Cauwenbergh, Eds.) - Plenum Publishing Corp., New York. pp. 35–41.Google Scholar
  9. 9.
    Raper K.B. and Fennell D.L. (1965): The Genus Aspergillus with a chapter on pathogenicity. - P.K.C. Austwick — The Williams & Wilkins Co., Baltimore.Google Scholar
  10. 10.
    Rebell G.L. and Forster R.K. (1981): Fungi of keratomycosis. In: Diagnostic Procedures for Bacterial, Mycotic and Parasitic Infections. 6th Edition, (A. Balows and W.J. Hausler, Jr., Eds.) -American Public Health Association, Washington.Google Scholar
  11. 11.
    Samson R.A. and Gams W. (1985): Typification of the species of Aspergillus and associated teleomorphs. In: Advances in Penicillium and Aspergillus Systematics. (R.A. Samson and J.I. Pitt, Eds.) Plenum Press, New York.Google Scholar
  12. 12.
    Stenson S., Brookner A. and Rosenthal S. (1983): Bilateral endogenous necrotizing scleritis due to Aspergillus oryzae. - Ann. Ophthal. 14: 67–72.Google Scholar
  13. 13.
    Wilhelmus K.R., Robinson N.M., Font R.A., Hamill M.B. and Jones D.B. (1988): Fungal keratitis in contact lens wearers. - Amer. J. Opthal. 106: 708–714.Google Scholar
  14. 14.
    Zimmerman L.E. (1962): Ocular mycoses. -Laboratory Investigation 11: 1151–1160.Google Scholar

Copyright information

© Kluwer Academic Publishers 1990

Authors and Affiliations

  • G. Coriglione
    • 1
  • G. Stella
    • 1
  • L. Gafa
    • 1
  • G. Spata
    • 1
  • S. Oliveri
    • 2
  • A. A. Padhye
    • 3
  • L. Ajello
    • 3
  1. 1.Ospedale Maria Paternò ArezzoRagusaItaly
  2. 2.Istituto di MicrobíologiaUniversità di CataniaCataniaItaly
  3. 3.Division of Mycotic Diseases, Centers for Disease Control, Public ServiceU.S. Department of Health and Human ServicesAtlantaU.S.A.

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