Traveller's diarrhea among Austrian tourists to warm climate countries: II. Clinical features
Abstract
The syndrome “Traveller's Diarrhea” (TD) is important for tourists travelling to warm-climate countries. In this study a worldwide survey on the clinical features of enteritis among 1,455 Austrian tourists is reported. The clinical parameters of TD show that this disease exhibits a very uniform clinical course which is not influenced by different regions with considerable differences in aetiology or by travel-associated parameters such as accomodation, travel style and individual dietary hygiene: TD starts mainly at the end of first week of the stay and the average duration of illness is 3.6+/−2.7 days. Watery and mucous stools were reported by 99% of patients with a frequency of 4 bowel movements per day, while bloody diarrhea occurred very rarely. However, 57.2% of patients suffered from abdominal cramps, less than one third of patients reported nausea and/or vomiting and fever accompanied the acute disease in 13%. Symptoms indicate that TD should not be considered a severe disease. The diarrheal illness will show the characteristics of an enteroinvasive disease only in rare cases. Treatment of TD is discussed: symptomatic or other nonantibiotic agents are preferable as antibiotics will only occasionally be necessary for treatment of an illness with a self-limiting character. For prophylaxis of TD, the preferable way to resolve the problem of TD in international travel, very few effective preparations are currently available, emphasizing the need for extensive research in this field.
Key words
Traveller's diarrhea Clinical features Aetiology Prophylaxis and treatmentPreview
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References
- 1.AdkinsH.J., EscamillaJ., SantiagoL.T., RanoaC., EcheverriaP. and CrossJ.H. (1987): Two-Year-Survey of etiologic agents of diarrheal disease at San Lazaro Hospital, Manila, Republic of the Philippines. -Journal of Clinical Microbiology 25: 1143–1147.Google Scholar
- 2.BlackR.E. (1986): Pathogenes that cause traveller's diarrhea in Latin-America and Africa. - Review of Infectious Disease 8: suppl. 2, S 131-S 135.Google Scholar
- 3.BriscoeJ. (1984): Intervention studies and the definition of dominant transmission routes. -American Journal of Epidemiology 120: 449–455.Google Scholar
- 4.Consensus conference: traveller's diarrhea (1985). -Journal of the American Medical Association 253: 2700–2704.Google Scholar
- 5.DuPontH.L. and HornickR.B. (1973): Adverse effects of Comotil therapy in Shigellosis. - Journal of the American Medical Association 226: 1525–1528.Google Scholar
- 6.DuPontH.L., SullivanP., PickeringL.K., HaynesC. and AckermannP.B. (1977): Symptomatic treatment of diarrhea with bismut subsalicylate among students attending a mexican university. - Gastroenterology 73: 715–718.Google Scholar
- 7.DuPontH.L., SullivanP., EvansD.G., PickeringC.K., EvansD.J., VolletJ.J., EricssonC.D., AckermannP.B. and TjoaW.S (1980): Prevention of traveller's diarrhea (Emporiatric Enteritis). Prophylactic administration of subsalicylate bismuth. - Journal of the American Medical Association 243: 237–241.Google Scholar
- 8.DuPontH.L., RevesR.R., GalindoE., SullivanP.S., WoodL.V. and MendiolaJ.G. (1982): Treatment of traveller's diarrhea with trimethoprim sulfomethoxazole and with trimethoprim alone. -New England Journal of Medicine 307: 841–844.Google Scholar
- 9.DuPontH.L., EricssonC.D., RevesR.R. and GalindoE. (1986): Antimicrobial therapy for traveller's diarrhea. - Rewiev of infectious disease 8: suppl. 2, S 217-S 222.Google Scholar
- 10.DuPontH.L. (1987): Treatment of acute traveller's diarrhea: a comparison of loperamide with Bismuthsubsalicylate. In: DuPontH.L. (ed.): acute infectious diarrhea: role of drug therapy. -Proceedings of an International Symposium, 9. International Congress of Infectious and Parasitic Diseases, Munich, 1986.Google Scholar
- 11.EricssonC.D., DuPontH.L. and JohnsonP.C. (1986): Nonantibiotic therapy for traveller's diarrhea. -Rewiev of Infectious Diseases 8: suppl. 2, S 202-S 206.Google Scholar
- 12.GorbachS.L. (1987): Bacterial diarrhea and its treatment. - Lancet ii: 1378–1382.Google Scholar
- 13.GraceyM., BurkeV. and RobinsonJ. (1982): Aeromonas-associated Gastroenteritis - Lancet ii: 1304–1306.Google Scholar
- 14.JohnsonP.C., EricssonC.D., DuPontH.L., MorganD.R.BitsuraJ.M. and WoodL.V. (1987): Comparison of Coperamide to Bismuth Subsalicylate for the treatment of acute traveller's diarrhea. - Journal of the American Medical Association 255: 757–762.Google Scholar
- 15.KeanB.H. (1986): Traveller's Diarrhea. An overview.- Reviews of Infectious Diseases 8: suppl. 2, S 111-S 116.Google Scholar
- 16.KollaritschH., ScheinerO., KremsnerP. and WiedermannG. (1989): Prevention of traveller's diarrhea: comparison of different non-antibiotic preparations for prophylaxis or treatment in double-blind trials among tourists. - Travel Medicine International, 7: 9–18.Google Scholar
- 17.LevineM.M. (1986): Antimicrobial therapy for infectious diarrhea. - Reviews of Infectious Diseases 8: suppl. 2, S 207-S 216.Google Scholar
- 18.MacDonaldK.L. and CohenM.L. (1986): Epidemiology of traveller's diarrhea: current perspectives. - Reviews of Infectious Diseases 8: suppl. 2, S 117-S 121.Google Scholar
- 19.PichlerH., DiridlG., SticklerK. and WolfD. (1986): Clinical efficacy of ciprofloxacin compared with placebo in bacterial diarrhea. - American Journal of Medicine 82: suppl. 4A, 329–332.Google Scholar
- 20.SteffenR., Van derLindeF., GyrK. and SchärM. (1983): Epidemiology of diarrhea in travellers. -Journal of the American Medical Association 249: 1176–1180.Google Scholar
- 21.SteffenR. (1984): Reisemedizin. Epidemiologie der Gesundheitsstörungen bei Interkontinentalreisenden und präventivmedizinische Konsequenzen. -Springer Verlag, Berlin-Heidelberg-New York-Tokio.Google Scholar
- 22.SteffenR. (1986): Epidemiologic studies of traveller's diarrhea, severe gastrointestinal infectious and cholera. - Reviews of Infectious Diseases 8: S 122-S 128.Google Scholar
- 23.SteffenR., HeusserR. and DuPontH.L. (1986): Prevention of traveller's diarrhea by nonantibiotic drugs. - Reviews of Infectious Diseases 8: suppl. 2, S 151-S 159.Google Scholar
- 24.SteffenR. and BoppartI. (1987): Traveller's diarrhea. -Ballieres Clinical Gastroenterology 1: 361–176.Google Scholar
- 25.SteffenR., HeusserR., HelmingerA. and SchärM. (1987): Preliminary results of a controlled study on the efficacy and side-effects of various agents in the therapy of traveller's diarrhea. In: DuPontH.L. (ed): acute infectious diarrhea: role of drug therapy. -Proceedings of an International Symposium, 9. International Congress of Infectious and Parasitic Diseases, Munich 1986.Google Scholar
- 26.SteffenR., MathewsonJ.J., EricssonC.D., DuPontH.L., HelmingerA., WalmT.K., WolffK. and VitassekF. (1988): Traveller's diarrhea in West-Africa and Mexico: fecal transport systems and liquid bismuth subsalicylate for self therapy. - The Journal of Infectious Diseases 157: 1008–1013.Google Scholar
- 27.TaylorD.N., EcheverriaP., BlaserM.J., PitarangsiC., BlacklowN., CrossJ. and WenigerB.G. (1985): Polymicrobial etiology of traveller's diarrhea. -Lancet i: 381–383.Google Scholar
- 28.TaylorD.N. and EcheverriaP. (1986): Etiology and epidemiology of traveller's diarrhea in Asia. -Reviews of Infectious Diseases 8: suppl. 2, S 136-S 141.Google Scholar
- 29.WolfeM.S. (1987): Acute infectious diarrhea: epidemiology, etiology and diagnosis. In: H.L.DuPont (ed.): acute infectious diarrhea: role of drug therapy. - Proceedings of an International Symposium, 9. International Congress of Infectious and Parasitic Diseases, Munich, 1986.Google Scholar