European Journal of Epidemiology

, Volume 4, Issue 2, pp 256–258

Immune response to hepatitis b vaccine given at different injection sites and by different routes a controlled randomized study

  • F. de Lalla
  • E. Rinaldi
  • D. Santoro
  • G. Pravettoni
Article

Abstract

Two-hundred-ninety-nine hospital workers were randomly allocated to receive MSD hepatitis B vaccine in different injection sites and by different routes (intramuscularly by gluteal or deltoid injections or subcutaneously in the arm) or Pasteur vaccine subcutaneously. Highest rates of seroconversion and highest mean anti-HBs titres were found in subjects given MSD vaccine by intramuscular injection into the deltoid muscle.

Key words

Hepatitis vaccine Immune response 

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Copyright information

© Kluwer Academic Publishers 1988

Authors and Affiliations

  • F. de Lalla
    • 1
  • E. Rinaldi
    • 1
  • D. Santoro
    • 1
  • G. Pravettoni
    • 2
  1. 1.Department of Infectious DiseasesS. Anna HospitalComoItaly
  2. 2.S. Pio X ClinicMilanItaly

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