Biotechnology Letters

, Volume 6, Issue 9, pp 549–554 | Cite as

Conversion of cephalosporin-c into 7-phenoxy-acetamido-cephalosporanic acid by acyltransferase of mutants of Penicillium chrysogenum

  • Rune Buhl Frederiksen
  • Claus Emborg


We have tested the acyl-transferase of penicillin producing strains and penicillin-less mutants of Penicillium chrysogenum for their ability to exchange the d-α-aminoadipic acid side chain of cephalosporin-C with phenoxyacetic acid. We found the reaction in both types of strains.


Organic Chemistry Penicillin Penicillium Penicillium Chrysogenum Phenoxyacetic Acid 
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Copyright information

© Science and Technology Letters 1984

Authors and Affiliations

  • Rune Buhl Frederiksen
    • 1
  • Claus Emborg
    • 1
  1. 1.Department of Applied BiochemistryThe Technical University of DenmarkLyngbyDenmark

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